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Life on Campus<br />

Mengqi Wang (left)<br />

and Rozita Abdoli<br />

Engineering a Cure<br />

Undergraduate students design <strong>the</strong>ir<br />

own experiments <strong>to</strong> address important<br />

medical questions<br />

NOT MANY UNDERGRADUATES can say <strong>the</strong>y’ve worked on finding<br />

a cure for cancer. But that’s exactly what two upper-year<br />

students at <strong>the</strong> Institute <strong>of</strong> Biomaterials and Biomedical<br />

Engineering did recently as part <strong>of</strong> an experiment <strong>the</strong>y<br />

designed and executed <strong>the</strong>mselves.<br />

The project, by Rozita Abdoli, a chemical engineering<br />

major, and Mengqi Wang, a specialist in electrical and<br />

computer engineering, examined<br />

“HeLa” or cervical cancer cells<br />

under stress. Their goal To find<br />

new ways <strong>to</strong> tackle <strong>the</strong> disease at<br />

<strong>the</strong> cellular level. In <strong>the</strong> end, <strong>the</strong><br />

study didn’t reveal as much as <strong>the</strong><br />

students had initially hoped, but it<br />

provided <strong>the</strong>m with a better understanding<br />

<strong>of</strong> <strong>the</strong> HeLa cell line,<br />

Wang observes.<br />

The study was one <strong>of</strong> several that<br />

third- and fourth-year undergrads<br />

at <strong>the</strong> institute shared recently with<br />

<strong>the</strong> public.<br />

Biomedical engineering majors<br />

Tara Strat<strong>to</strong>n and Andrea Pagot<strong>to</strong><br />

looked at ways <strong>to</strong> amplify and tag<br />

DNA sequences <strong>of</strong> E. coli bacteria<br />

<strong>to</strong> find an easier way for scientists<br />

<strong>to</strong> test for <strong>the</strong> deadly organism<br />

in freshwater samples. The methods used showed promise,<br />

<strong>the</strong>y say.<br />

Richard Gao and Om Bhatt, engineering science specialists,<br />

studied <strong>the</strong> adverse effects <strong>of</strong> electrical fields on two<br />

different stem cell lines. Their study found that many stem<br />

cells die when exposed <strong>to</strong> an amplified electrical field.<br />

Unlike courses where <strong>the</strong> right answer is <strong>the</strong> only answer,<br />

courses that include major design projects allow students<br />

<strong>to</strong> learn through trial and error – like real scientists do.<br />

“Theory is best learned when our students have <strong>the</strong> opportunity<br />

<strong>to</strong> apply <strong>the</strong>ir classroom knowledge <strong>to</strong> real-world<br />

engineering challenges that have <strong>the</strong> potential <strong>to</strong> make an<br />

impact,” says Pr<strong>of</strong>. Paul Santerre, <strong>the</strong> institute’s direc<strong>to</strong>r.<br />

“That’s what our students have aspired <strong>to</strong> in this course.”<br />

– ERIN VOLLICK<br />

Help us reduce waste!<br />

Are you <strong>the</strong> intended recipient <strong>of</strong> this copy <strong>of</strong> U <strong>of</strong> T Magazine<br />

If not, please have <strong>the</strong> name removed from our mailing list by calling<br />

1-800-463-6048 or by sending an email message <strong>to</strong><br />

address.update@u<strong>to</strong>ron<strong>to</strong>.ca<br />

PHOTO: ERIN VOLLICK<br />

summer 2012 17

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