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Autonomic Nervous System

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BIMM118<br />

Cholinergic <strong>System</strong> - Agonists<br />

Acetylcholinesterase Inhibitors<br />

• “Horny goat weed”<br />

– Epimedium sagittatum<br />

– Acts as AcCh-esterase inhibitor (active ingredient unknown)<br />

– Indirect stimulation of vascular M3 receptors triggers NO production => vasodilation<br />

(action similar to Sildenafil (Viagra®), which potentiates NO effects)

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