Autonomic Nervous System
Autonomic Nervous System
Autonomic Nervous System
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BIMM118<br />
Cholinergic <strong>System</strong> - Antagonists<br />
Nicotinic Parasympatholytics<br />
Nondepolarizing blockers<br />
• Curare:<br />
– Plant derived arrow poison in S-America<br />
– Active ingredient is d-Tubocurarine<br />
– Death occurs through respiratory paralysis<br />
– Tubocurarine is not absorbed orally => no risk eating the prey<br />
– Tubocurarine was used clinically as muscle relaxant during surgery<br />
but: Tubocurarine triggers histamine release => blood pressure drops
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