The Molecular Pathogenesis of Cancer Joan Brugge Cell Biology ...

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What Causes Breast Cells to Change their Behavior Different types of breast tumors contain mutations in different genes.
Most Cancers Contain Gross Chromosomal Aberrations Amplifications Deletions 5 4 3 2 1 0 -1 -2 -3 Comparative Genome Hybridization
Page 1 and 2: The Molecular Pathogenesis of Cance
Page 3 and 4: Challenge: To Identify the Achilles
Page 5 and 6: Different Stages and Grades of Brea
Page 7: Initiation and Progression of Breas
Page 11 and 12: Role of Proteins in Cells Proteins
Page 13 and 14: Initiation and Progression of Breas
Page 15 and 16: “Genomics” Approaches
Page 17 and 18: Which of the 100’s of Altered Gen
Page 19 and 20: Model of Breast Epithelial Acini ht
Page 21 and 22: Reconstruction of Tumor Phenotype G
Page 23 and 24: Laboratory Cancer Model Normal stru
Page 25 and 26: HER2 Induces Structures that Resemb
Page 27 and 28: Pathways to Luminal Filling Bcl-2/B
Page 29 and 30: Ran Expression Induces an Invasive
Page 31 and 32: Designer Drugs- Hope for the Future
Page 33 and 34: Anti-Estrogen Therapy Estrogen x x
Page 35 and 36: HELP! • Get students excited abou
Page 37 and 38: How do Our Genes Get Mutated • So
Page 39: Non-genetic Factors that Influence

The Molecular Pathogenesis of Cancer Joan Brugge Cell Biology ...

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