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Nicotine replacement therapy … - Carlos A ... - Entretiens du Carla

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Conclusion 7<br />

Oral form or Patches for re<strong>du</strong>cing<br />

tobacco consumption<br />

To be effective, re<strong>du</strong>ction in<br />

consumption has to be supported by NRT.<br />

Oral forms are to be selected as a priority<br />

in accordance with the smoker’s<br />

preferences. Patches and oral forms may<br />

also be combined.<br />

One should be aware of a high(er) level<br />

of nicotinemia when NRT is used for<br />

re<strong>du</strong>cing smoking when the smoker at the<br />

same time is not re<strong>du</strong>cing the amount of<br />

cigarettes as planned.<br />

The experts indicate that oral tobacco<br />

pro<strong>du</strong>cts used in certain countries such as<br />

snus, to re<strong>du</strong>ce the consumption of<br />

cigarettes carry the risk of causing somatic<br />

pathologies and addiction, and therefore<br />

must be the subject of further studies<br />

before public authorities can authorize<br />

their sale. See Conclusion 14.<br />

Conclusion 8<br />

Re<strong>du</strong>ction and pregnancy<br />

As much of the harm that smoking causes<br />

in pregnancy is dose dependant (e.g.<br />

re<strong>du</strong>ced birth weight), pregnant women<br />

should try to quit when they are pregnant<br />

and if they cannot stop smoking, they should<br />

re<strong>du</strong>ce their smoking as much as possible. If,<br />

using only behavioural methods, women are<br />

not able to stop smoking then they could<br />

consider using nicotine <strong>replacement</strong> <strong>therapy</strong><br />

(NRT) to help them stop (see Conclusion 12).<br />

Much of the toxicity from tobacco use<br />

<strong>du</strong>ring pregnancy may be caused by the<br />

pro<strong>du</strong>cts of combustion* (see note in the<br />

margin) that are given off when tobacco is<br />

burned (e.g. carbon monoxide or polycyclic<br />

aromatic hydrocarbons) and so NRT may be<br />

safer than continued smoking.<br />

11<br />

However, the impact on women’s total<br />

nicotine exposure (i.e. from both NRT and<br />

continued smoking), of using NRT for<br />

smoking re<strong>du</strong>ction in pregnancy remains<br />

unknown. Research is needed to determine<br />

whether or not using NRT to help re<strong>du</strong>ce<br />

(and not quit) smoking in pregnancy also<br />

re<strong>du</strong>ces the delivery of toxins and is less<br />

harmful to the fetus than continued<br />

maternal smoking.<br />

Conclusion 9<br />

Re<strong>du</strong>ction in a patient with heart<br />

disease<br />

Many studies have confirmed the perfect<br />

safety of NRT in association with a re<strong>du</strong>ction<br />

in tobacco consumption for patients with<br />

heart diseases (including coronary patients).<br />

Also, even it is important to emphasize<br />

the necessity of total abstinence for smokers<br />

with heart disease to minimize health risks<br />

from tobacco, re<strong>du</strong>ction should eventually<br />

be promoted as a first step to achieving<br />

cessation in smokers unwilling or perceiving<br />

themselves unable to quit. Nevertheless, we<br />

don't know the real benefits of this strategy<br />

on health outcomes, especially in coronary<br />

patients.<br />

These recommendations confirm the high<br />

tolerance of NRT and their usefulness as<br />

excellent tools to help stop and re<strong>du</strong>ce<br />

tobacco use. They also stress the importance<br />

of supporting smokers and highlight the key<br />

role of the physician or another health<br />

worker or tobaccologist who must adjust the<br />

choice of <strong>therapy</strong> in order to meet the<br />

smoker’s needs and possibilities.<br />

Le <strong>Carla</strong>.<br />

Conclusions<br />

* It is not<br />

definite that<br />

carbon monoxyde<br />

is the<br />

primary cause<br />

of harm from<br />

smoking in<br />

pregnancy.

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