HAIR STYLING PATENTS FOR 2006 - Patent and Intellectual ...

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agent and having a physiologically tolerable pH value. Pain relief was achieved with applied
amounts of clonidine in the range of about 2 milligrams per day to about 6 mg per day.
US Patent No: 6150413
Triaromatic compounds and pharmaceutical/cosmetic compositions comprised thereof
Novel pharmaceutically/cosmetically-active triaromatic compounds have the structural formula (I):
##STR1## and are useful for the treatment of a wide variety of disease states, whether human or
veterinary, for example dermatological, rheumatic, respiratory, cardiovascular, bone and
ophthalmological disorders, as well as for the treatment of mammalian skin and hair
conditions/disorders.
US Patent No: 6150459
Comb polymers for regulating cell surface interactions
Synthetic comb copolymers which elicit controlled cellular response, methods of applying these
polymers to various surfaces, and methods of using the polymers for modifying biomaterial
surfaces, in tissue engineering applications and as drug delivery devices are provided. The comb
copolymers are comprised of hydrophobic polymer backbones and hydrophilic, non-cell binding
side chains which can be end-capped with cell-signaling ligands that guide cellular response. By
mixing non-cell binding combs with ligand-bearing combs, the surface concentration and spatial
distribution of one or more types of ligands, including adhesion peptides and growth factors, can be
tuned on a surface to achieve desired cellular response. In one embodiment, the combs are used as
stabilizing agents for dispersion polymerization of latexes. The comb-stabilized latexes can be
applied to substrates by standard coating operations to create a bioregulating surface, or used as
drug delivery agents. In another embodiment, the combs can be blended in small quantities to a
hydrophobic matrix polymer and processed to affect the surface segregation of the comb. The comb
copolymers are formed in one embodiment by providing a biodegradable polyester backbone that
includes reactive groups, and reacting the reactive groups in the backbone with reactive chain ends
on a low molecular weight hydrophilic polymer. In another embodiment, non-biodegradable comb
copolymers are formed by free radical synthesis of a hydrophobic monomer and a hydrophilic
macromonomer. In all of the above embodiments, a portion of the hydrophilic polymer side chains
can be covalently coupled to cell-signaling ligands such as adhesion peptides or growth factors to
control cellular response.
US Patent No: 6156750
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