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Vector-borne Infectious Diseases in Pakistan

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16<br />

Mur<strong>in</strong>e Typhus,<br />

Endemic Typhus Fever<br />

Epidemic Relaps<strong>in</strong>g<br />

Fever<br />

Rickettsia typhi<br />

Borrelia<br />

recurrentis<br />

Transmission: Intake of<br />

<strong>in</strong>fectious rodent flea<br />

material (cellular or fecal)<br />

Primary vectors:<br />

Xenopsylla astia (rat flea),<br />

X. cheopis (southern rat<br />

flea), Pulex irritans<br />

(human flea)<br />

Secondary <strong>Vector</strong>s:<br />

Other flea species<br />

Reservoirs:<br />

Rats harbor<strong>in</strong>g the<br />

enzootic vector Polyplax<br />

sp<strong>in</strong>ulosa (rat louse),<br />

Ornithonyssus bacoti<br />

(tropical rat mite)<br />

Transmission: By<br />

scratch<strong>in</strong>g of <strong>in</strong>fected<br />

body louse material <strong>in</strong>to<br />

dependent on the socioeconomic<br />

environment<br />

(i.e., refugees, refugee<br />

camps)<br />

Transmission period:<br />

Year round <strong>in</strong> cases of rat<br />

<strong>in</strong>festation<br />

Incidence and<br />

seroprevalence:<br />

Endemic nationwide<br />

except for the extreme<br />

north and south; no<br />

additional epidemiological<br />

data are available at this<br />

time<br />

Bite properties: Rat fleas<br />

are nest specific, not host<br />

specific; all animal fleas<br />

also bite humans; fleas<br />

survive approx. 10 days<br />

without a blood meal, up<br />

to two months <strong>in</strong> low<br />

temperatures; transmission<br />

of the agent occurs by<br />

<strong>in</strong>halation or by absorption<br />

(scratch<strong>in</strong>g) of <strong>in</strong>fectious<br />

flea material (crushed<br />

fleas or flea feces) <strong>in</strong>to<br />

wounds<br />

Transmission period:<br />

Predom<strong>in</strong>antly dur<strong>in</strong>g the<br />

w<strong>in</strong>ter months from Dec. -<br />

Preventive measures:<br />

- Indoors: Regular<br />

eradication of rats and<br />

clean<strong>in</strong>g of build<strong>in</strong>gs<br />

- Outdoors: Flea control<br />

with subsequent rat and<br />

rodent control (urban<br />

rodent plague)<br />

Preventive measures:<br />

- In endemic and<br />

epidemic regions:

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