Vector-borne Infectious Diseases in Pakistan
Vector-borne Infectious Diseases in Pakistan
Vector-borne Infectious Diseases in Pakistan
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16<br />
Mur<strong>in</strong>e Typhus,<br />
Endemic Typhus Fever<br />
Epidemic Relaps<strong>in</strong>g<br />
Fever<br />
Rickettsia typhi<br />
Borrelia<br />
recurrentis<br />
Transmission: Intake of<br />
<strong>in</strong>fectious rodent flea<br />
material (cellular or fecal)<br />
Primary vectors:<br />
Xenopsylla astia (rat flea),<br />
X. cheopis (southern rat<br />
flea), Pulex irritans<br />
(human flea)<br />
Secondary <strong>Vector</strong>s:<br />
Other flea species<br />
Reservoirs:<br />
Rats harbor<strong>in</strong>g the<br />
enzootic vector Polyplax<br />
sp<strong>in</strong>ulosa (rat louse),<br />
Ornithonyssus bacoti<br />
(tropical rat mite)<br />
Transmission: By<br />
scratch<strong>in</strong>g of <strong>in</strong>fected<br />
body louse material <strong>in</strong>to<br />
dependent on the socioeconomic<br />
environment<br />
(i.e., refugees, refugee<br />
camps)<br />
Transmission period:<br />
Year round <strong>in</strong> cases of rat<br />
<strong>in</strong>festation<br />
Incidence and<br />
seroprevalence:<br />
Endemic nationwide<br />
except for the extreme<br />
north and south; no<br />
additional epidemiological<br />
data are available at this<br />
time<br />
Bite properties: Rat fleas<br />
are nest specific, not host<br />
specific; all animal fleas<br />
also bite humans; fleas<br />
survive approx. 10 days<br />
without a blood meal, up<br />
to two months <strong>in</strong> low<br />
temperatures; transmission<br />
of the agent occurs by<br />
<strong>in</strong>halation or by absorption<br />
(scratch<strong>in</strong>g) of <strong>in</strong>fectious<br />
flea material (crushed<br />
fleas or flea feces) <strong>in</strong>to<br />
wounds<br />
Transmission period:<br />
Predom<strong>in</strong>antly dur<strong>in</strong>g the<br />
w<strong>in</strong>ter months from Dec. -<br />
Preventive measures:<br />
- Indoors: Regular<br />
eradication of rats and<br />
clean<strong>in</strong>g of build<strong>in</strong>gs<br />
- Outdoors: Flea control<br />
with subsequent rat and<br />
rodent control (urban<br />
rodent plague)<br />
Preventive measures:<br />
- In endemic and<br />
epidemic regions: