Vector-borne Infectious Diseases in Pakistan
Vector-borne Infectious Diseases in Pakistan
Vector-borne Infectious Diseases in Pakistan
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20<br />
Leptospirosis Leptospira<br />
icterohaemorrhagiae,<br />
Leptospira ssp.<br />
Cutaneous<br />
Leishmaniasis<br />
Leishmania<br />
tropica major<br />
Transmission: Via<br />
contam<strong>in</strong>ated water<br />
through active sk<strong>in</strong><br />
penetration by the bacteria<br />
(agrarian mode of<br />
transmission), as well as<br />
through contact with<br />
<strong>in</strong>fectious rodent ur<strong>in</strong>e<br />
and animal material<br />
(rural/urban by rodent<br />
<strong>in</strong>festation or <strong>in</strong>fected<br />
livestock)<br />
Primary vectors:<br />
Brown rat (Rattus<br />
norvegicus), hogs, mice,<br />
livestock<br />
Secondary vectors:<br />
Other mammals<br />
Reservoirs:<br />
Rats, other mammals<br />
Transmission: Sand fly<br />
bite<br />
Transmission period:<br />
Year-round<br />
Incidence and<br />
seroprevalence: Endemic<br />
nationally; seroprevalence<br />
<strong>in</strong> <strong>Pakistan</strong>i soldiers 1-6%<br />
(1996); 11% of patients<br />
with non-A non-B<br />
hepatitis had acute<br />
antibody levels aga<strong>in</strong>st<br />
leptospires (1996); no<br />
further epidemiological<br />
data are available at this<br />
time<br />
Mode of transmission:<br />
- Special note:<br />
micromicturition of<br />
<strong>in</strong>fected synanthropic<br />
rodents, such as rats,<br />
which constantly emit<br />
ur<strong>in</strong>e <strong>in</strong> t<strong>in</strong>y droplets.<br />
Leptospiral reservoirs<br />
spread the agent very<br />
efficiently over large<br />
areas; therefore, after<br />
rodents have been<br />
successfully cleared from<br />
an area, dis<strong>in</strong>fection of the<br />
entire area must be<br />
considered<br />
Transmission period:<br />
Year-round with a peak<br />
Preventive measures:<br />
- Avoid contam<strong>in</strong>ated<br />
waters<br />
- Rat and rodent control<br />
over a large area around<br />
the camp with subsequent<br />
surface dis<strong>in</strong>fection<br />
- M<strong>in</strong>imize contact with<br />
livestock<br />
Preventive measures:<br />
- Indoors: Use