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Vector-borne Infectious Diseases in Pakistan

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20<br />

Leptospirosis Leptospira<br />

icterohaemorrhagiae,<br />

Leptospira ssp.<br />

Cutaneous<br />

Leishmaniasis<br />

Leishmania<br />

tropica major<br />

Transmission: Via<br />

contam<strong>in</strong>ated water<br />

through active sk<strong>in</strong><br />

penetration by the bacteria<br />

(agrarian mode of<br />

transmission), as well as<br />

through contact with<br />

<strong>in</strong>fectious rodent ur<strong>in</strong>e<br />

and animal material<br />

(rural/urban by rodent<br />

<strong>in</strong>festation or <strong>in</strong>fected<br />

livestock)<br />

Primary vectors:<br />

Brown rat (Rattus<br />

norvegicus), hogs, mice,<br />

livestock<br />

Secondary vectors:<br />

Other mammals<br />

Reservoirs:<br />

Rats, other mammals<br />

Transmission: Sand fly<br />

bite<br />

Transmission period:<br />

Year-round<br />

Incidence and<br />

seroprevalence: Endemic<br />

nationally; seroprevalence<br />

<strong>in</strong> <strong>Pakistan</strong>i soldiers 1-6%<br />

(1996); 11% of patients<br />

with non-A non-B<br />

hepatitis had acute<br />

antibody levels aga<strong>in</strong>st<br />

leptospires (1996); no<br />

further epidemiological<br />

data are available at this<br />

time<br />

Mode of transmission:<br />

- Special note:<br />

micromicturition of<br />

<strong>in</strong>fected synanthropic<br />

rodents, such as rats,<br />

which constantly emit<br />

ur<strong>in</strong>e <strong>in</strong> t<strong>in</strong>y droplets.<br />

Leptospiral reservoirs<br />

spread the agent very<br />

efficiently over large<br />

areas; therefore, after<br />

rodents have been<br />

successfully cleared from<br />

an area, dis<strong>in</strong>fection of the<br />

entire area must be<br />

considered<br />

Transmission period:<br />

Year-round with a peak<br />

Preventive measures:<br />

- Avoid contam<strong>in</strong>ated<br />

waters<br />

- Rat and rodent control<br />

over a large area around<br />

the camp with subsequent<br />

surface dis<strong>in</strong>fection<br />

- M<strong>in</strong>imize contact with<br />

livestock<br />

Preventive measures:<br />

- Indoors: Use

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