Advanced statistical analysis of epidemiological studies
Advanced statistical analysis of epidemiological studies
Advanced statistical analysis of epidemiological studies
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Results.<br />
Josefsson et al., Lancet, 2000, 355, 2189-93.<br />
Viral load Cases/controls exp(β)<br />
HPV 16 negative 354/578 1<br />
Below 20 percentile 16/15 1.9 (0.8-4.2)<br />
20-40 percentile 23/7 7.2 (2.7-19.1)<br />
40-60 percentile 28/3 22.8 (5.5-95.0)<br />
60-80 percentile 27/4 18.9 (5.5-64.9)<br />
Above 80 percentile 30/1 59.0 (7.5-462.2)<br />
Dose-response effect <strong>of</strong> viral load on rate <strong>of</strong> CIS (here: based on first<br />
smear, only).<br />
In this study (and in many other nested c-c <strong>studies</strong>): possible to<br />
estimate absolute risk.<br />
40