Study Design Streptococcal Cell Wall Induced Arthritis - MorphoSys
Study Design Streptococcal Cell Wall Induced Arthritis - MorphoSys
Study Design Streptococcal Cell Wall Induced Arthritis - MorphoSys
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MOR103 Antibody Stage Outcome<br />
� Generation of a fully human antibody �<br />
� High affinity to human GM-CSF �<br />
� Inhibition of GM-CSF mediated cellular mechanisms �<br />
� No off target cross-reactivity �<br />
� Binds rhesus and rat GM-CSF �<br />
� Demonstrable efficacy in an established RA model �<br />
� Safe and well tolerated with dose dependent PK �<br />
� PER.C6 ® cell derived drug product �<br />
16<br />
HAH, New York, Nov 2008 | © <strong>MorphoSys</strong> AG
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