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Annual Report 2009 - Daiichi Sankyo

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SALES AND MARKETING OPERATIONS<br />

Prescription Drug Business<br />

Japan<br />

Market Trends<br />

In fiscal 2008, the Japanese prescription drug market expanded<br />

due to the growing prevalence of lifestyle diseases and progressive<br />

demographic graying, despite the impact of various negative<br />

factors—including an additional change in prescription format<br />

designed to encourage the use of generic drugs, an increased<br />

number of hospitals applying the diagnosis procedure combination<br />

(DPC) reimbursement system, and other intensified government<br />

efforts to restrain drug-related expenditures through systemic<br />

reforms as well as other factors such as drug price revision under<br />

the National Health Insurance (NHI) scheme. The market had a<br />

noteworthy boost from the increasing use of innovative pharmaceuticals<br />

such as antibody drugs. Amid these conditions, <strong>Daiichi</strong><br />

<strong>Sankyo</strong>’s domestic net sales of prescription drugs amounted to<br />

¥406.7 billion, down 4.8% from the fiscal 2007 level. Although<br />

sales of flagship products centering on Olmetec grew, overall<br />

sales decreased due to factors such as lower sales of long-selling<br />

products and the transfer of marketing rights for Zantac and<br />

Coversyl.<br />

Evolution of the MR Crosswise System<br />

<strong>Daiichi</strong> <strong>Sankyo</strong>’s MR Crosswise system (“MR” refers to marketing<br />

representatives, or sales representatives) is designed to effectively<br />

provide medical professionals with information on each therapeutic<br />

area based on collaboration between two types of sales representatives.<br />

Under this system, some sales representatives maintain<br />

high levels of specialized knowledge in therapeutic areas such as<br />

cardiovascular diseases and oncology, while other sales representatives<br />

are responsible for understanding and meeting the special<br />

needs of individual medical facilities. The first system of its type in<br />

Japan, the MR Crosswise structure organically integrates <strong>Daiichi</strong><br />

<strong>Sankyo</strong>’s sales force, which is among the biggest in Japan, to create<br />

an organization capable of providing medical professionals<br />

with high-quality information in a timely manner. Through this<br />

structure, the Company’s sales representatives have been earning<br />

high overall ratings from outside evaluation institutions.<br />

To meet the increasingly diverse needs of medical institutions,<br />

<strong>Daiichi</strong> <strong>Sankyo</strong> will continue to promote the further evolution of the<br />

MR Crosswise system, and shift from the conventional one-sided<br />

provision of information to a more bilateral approach involving<br />

additional efforts to elicit and respond to the ideas of medical<br />

professionals.<br />

Performance of Principal Products<br />

Cardiovascular Diseases: Angiotensin II receptor blockers<br />

(ARBs) are a growing sector of the Japanese drug market, and<br />

sales of our flagship antihypertensive agent Olmetec (generic<br />

name Olmesartan) grew more than those of any other single ARB<br />

product. Olmetec sales jumped 16.6% over the fiscal 2007 level,<br />

to ¥64.4 billion, despite a price reduction due to Japan’s drug<br />

price system revision, in response to ARB market expansion.<br />

Conditions in the ARB market continue to be harsh due to the<br />

entry of competitors as well as fixed-dose combination antihypertensive<br />

agents, but Olmetec is considered to be a best-in-class<br />

product owing to its strong efficacy in reducing blood pressure<br />

and superior performance in protecting internal organs. In view of<br />

these benefits, the Pharmaceutical Society of Japan selected<br />

Olmetec as the winner of its Award for Drug Research and<br />

Development in 2008. To further increase the value of Olmetec,<br />

we will generate additional scientific evidence related to its performance<br />

and contribute to the health of even more patients in the<br />

future.<br />

Net Sales of Key Products (¥ billion)<br />

80<br />

60<br />

Olmetec<br />

Antihypertensive (ARB)<br />

55.2<br />

64.4<br />

Mevalotin<br />

Antihyperlipidemic agent<br />

75.2<br />

67.8<br />

61.6<br />

Cravit<br />

Synthetic antibacterial agent<br />

50.7 50.2 46.7 47.4 43.0<br />

29.0 30.9 33.6 38.7 34.7 31.5 31.2 28.3<br />

Loxonin<br />

Anti-inflammatory analgesic<br />

Omnipaque<br />

Contrast agent<br />

40<br />

42.2<br />

20<br />

25.6<br />

0<br />

(FY) 2005 2006 2007 2008 2005 2006 2007 2008 2005 2006 2007 2008 2005 2006 2007 2008 2005 2006 2007 2008<br />

24<br />

<strong>Daiichi</strong> <strong>Sankyo</strong> Co., Ltd. <strong>Annual</strong> <strong>Report</strong> <strong>2009</strong>

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