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Opsporen in surveillance stalen - UZ Leuven

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Derepressed of plasmid-mediated AmpC confirmatie:<br />

5. Disk potentiatie test<br />

– AmpC <strong>in</strong>hibitor= boorzuur<br />

– Betrouwbaar voor confirmatie plasmid-mediated AmpC productie 20-26<br />

• ! Verschillen <strong>in</strong> study design<br />

– # & type <strong>in</strong>dicator cefalospor<strong>in</strong>e<br />

– hoeveelheid <strong>in</strong>hibitor toegevoegd<br />

– Nood aan bijkomend onderzoek:<br />

• beste disk potentiation test configuratie<br />

• <strong>in</strong> derepressed AmpC producers<br />

– Nadeel: niet commercieel beschikbaar<br />

20. Tenover FC, J Cl<strong>in</strong> Microbiol. 2009.<br />

21. Coudron PE, J. Cl<strong>in</strong> Microbiol. 2005.<br />

22. Yagi T, J Cl<strong>in</strong> Microbiol. 2005.<br />

23. Brenwald NP, J Antimicrob Chemother. 2005.<br />

24. Lee W, Korean J Lab Med. 2009.<br />

25. Tan TY, Antimicrob Agents Chemother. 2009.

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