Opsporen in surveillance stalen - UZ Leuven
Opsporen in surveillance stalen - UZ Leuven
Opsporen in surveillance stalen - UZ Leuven
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Metallo-bèta lactamases<br />
Confirmatie <strong>in</strong> Enterobacteriaceae, P. aerug<strong>in</strong>osa, Ac<strong>in</strong>etobacter<br />
2. Inhibitor based confirmatie testen<br />
i. Cica-Beta test<br />
ii. MBL Etest ® (IP/IPI)<br />
iii. DDST & CDDST<br />
– Meest volledige studie<br />
– Rosco’s KPC+MBL ConfirmID kit<br />
» Indicator= MEM, <strong>in</strong>hibitor= DPA*<br />
» Enkel geëvalueerd <strong>in</strong> MBL produc<strong>in</strong>g Enterobacteriaceae<br />
» SN= 100% (<strong>in</strong>cl. MEM gevoelige stammen)<br />
– Rosco’s CDDST met IMP & EDTA<br />
» Geëvalueerd <strong>in</strong> MBL-produc<strong>in</strong>g P. aerug<strong>in</strong>osa & Ac<strong>in</strong>etobacter spp<br />
» SN= 100%, lage specificiteit<br />
*dipicol<strong>in</strong>ic acid
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