- Page 2 and 3: Introduction In the quarter-century
- Page 4 and 5: INTRODUCTION 3 equipment ordered ov
- Page 8 and 9: INTRODUCTION 7 led to new medicine
- Page 10 and 11: INTRODUCTION 9 Moreover, big pharma
- Page 12 and 13: PART ONE BIOHYPE
- Page 14 and 15: 14 BIOHYPE years of halting progres
- Page 16 and 17: 16 BIOHYPE mustard gas, which the a
- Page 18 and 19: 18 BIOHYPE properly. Miyake didn’
- Page 20 and 21: 20 BIOHYPE to work with. Luckily, b
- Page 22 and 23: 22 BIOHYPE San Francisco and Boston
- Page 24 and 25: 24 BIOHYPE nology behind recombinan
- Page 26 and 27: 26 BIOHYPE three of the protein’s
- Page 28 and 29: 28 BIOHYPE 1983, he changed his min
- Page 30 and 31: 30 BIOHYPE relationship with a miss
- Page 32 and 33: 32 BIOHYPE million to develop. Yet
- Page 34 and 35: 34 BIOHYPE the lower dose three tim
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- Page 38 and 39: 38 BIOHYPE products to technologica
- Page 40 and 41: 40 BIOHYPE Over the years, the fede
- Page 42 and 43: 42 BIOHYPE NIH clinics under his tu
- Page 44 and 45: 44 BIOHYPE a patient to make him be
- Page 46 and 47: 46 BIOHYPE extremely low doses of t
- Page 48 and 49: 48 BIOHYPE include the office visit
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- Page 54 and 55: 54 BIOHYPE was cystic fibrosis, a g
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56 BIOHYPE announced plans to start
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58 BIOHYPE approach. He suffered pe
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60 BIOHYPE chance to pursue enzyme
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62 BIOHYPE more awe for the complex
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64 BIOHYPE sector to compete at all
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66 BIOHYPE reporters on Human Genom
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68 BIOHYPE in the 1970s when he cam
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70 BIOHYPE Before he left, Hunkapil
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72 BIOHYPE bomb survivors. Other ag
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74 BIOHYPE By early 1996, DOE offic
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76 BIOHYPE hundred of the new machi
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78 BIOHYPE nal business plan. But t
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80 BIOHYPE that secure the revenues
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82 BIOHYPE of the National Academy
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4 A Public-Private Partnership The
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A PUBLIC-PRIVATE PARTNERSHIP 87 ues
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A PUBLIC-PRIVATE PARTNERSHIP 89 For
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A PUBLIC-PRIVATE PARTNERSHIP 91 per
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A PUBLIC-PRIVATE PARTNERSHIP 93 sta
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A PUBLIC-PRIVATE PARTNERSHIP 95 198
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A PUBLIC-PRIVATE PARTNERSHIP 97 Thr
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A PUBLIC-PRIVATE PARTNERSHIP 99 squ
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A PUBLIC-PRIVATE PARTNERSHIP 101 ho
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A PUBLIC-PRIVATE PARTNERSHIP 103 On
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A PUBLIC-PRIVATE PARTNERSHIP 105 al
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A PUBLIC-PRIVATE PARTNERSHIP 107 Si
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A PUBLIC-PRIVATE PARTNERSHIP 109 hi
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A PUBLIC-PRIVATE PARTNERSHIP 111 ta
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A PUBLIC-PRIVATE PARTNERSHIP 113 wo
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5 The Divorce Hoffmann-La Roche’s
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THE DIVORCE 117 oriented board recr
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THE DIVORCE 119 researchers to supp
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THE DIVORCE 121 bilities and instal
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THE DIVORCE 123 obtained more data
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THE DIVORCE 125 and he would have t
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THE DIVORCE 127 complained that the
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THE DIVORCE 129 ernment funding for
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THE DIVORCE 131 being made on the p
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THE DIVORCE 133 AIDS activists to s
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THE DIVORCE 135 By the end of July,
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6 Breakthrough! Combination therapy
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BREAKTHROUGH! 139 Born in mainland
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BREAKTHROUGH! 141 tions along the p
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BREAKTHROUGH! 143 pany didn’t hav
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BREAKTHROUGH! 145 marker at that ti
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BREAKTHROUGH! 147 in a joint letter
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BREAKTHROUGH! 149 for at least a ye
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BREAKTHROUGH! 151 activity. But thr
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BREAKTHROUGH! 153 trol it. Yet ther
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BREAKTHROUGH! 155 third-stage trial
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BREAKTHROUGH! 157 pharmaceutical co
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BREAKTHROUGH! 159 much more than $1
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BREAKTHROUGH! 161 annual death toll
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BREAKTHROUGH! 163 The results of th
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THE FAILED CRUSADE 165 Why NCI-fund
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THE FAILED CRUSADE 167 Cancer thera
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THE FAILED CRUSADE 169 Great academ
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THE FAILED CRUSADE 171 aged his mos
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THE FAILED CRUSADE 173 Rhoads was d
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THE FAILED CRUSADE 175 job as an in
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THE FAILED CRUSADE 177 to cancer. B
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THE FAILED CRUSADE 179 in support o
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THE FAILED CRUSADE 181 accounted fo
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THE FAILED CRUSADE 183 genetic rese
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THE FAILED CRUSADE 185 For a brief
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THE FAILED CRUSADE 187 was no evide
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THE FAILED CRUSADE 189 Taxol, cance
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THE FAILED CRUSADE 191 “hundreds
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THE FAILED CRUSADE 193 the way of r
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THE FAILED CRUSADE 195 school child
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THE FAILED CRUSADE 197 by Genentech
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THE FAILED CRUSADE 199 ment to find
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THE FAILED CRUSADE 201 the Wall Str
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THE FAILED CRUSADE 203 screen in th
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THE FAILED CRUSADE 205 cessful, whi
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PART THREE BIG PHARMA
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210 BIG PHARMA handful of cures (an
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212 BIG PHARMA The pattern happened
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214 BIG PHARMA In a series of heari
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216 BIG PHARMA weren’t convinced
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218 BIG PHARMA The first industry s
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220 BIG PHARMA ple pill (the color
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222 BIG PHARMA and Prilosec. They a
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224 BIG PHARMA scientists took apar
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226 BIG PHARMA generic painkillers.
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228 BIG PHARMA of gastrointestinal
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230 BIG PHARMA Before turning to th
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232 BIG PHARMA from the days when t
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234 BIG PHARMA copayment if they pu
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236 BIG PHARMA of Illinois at Chica
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238 BIG PHARMA for Allergies and In
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240 BIG PHARMA the particular finan
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242 BIG PHARMA budgets had been hal
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244 BIG PHARMA blockbusters, the dr
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246 BIG PHARMA The Global Alliance
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248 BIG PHARMA cines. While a major
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250 BIG PHARMA people who have dedi
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252 BIG PHARMA often see potential
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254 BIG PHARMA lar is already in pl
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256 BIG PHARMA dysfunction drug, wh
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258 BIG PHARMA Foundation and the f
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260 BIG PHARMA teen to twenty years
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262 NOTES TO PAGES 16-34 2. The upd
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264 NOTES TO PAGES 45-57 enzyme are
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266 NOTES TO PAGES 71-90 18. Gossel
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268 NOTES TO PAGES 108-125 31. Inte
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270 NOTES TO PAGES 138-153 2. Inter
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272 NOTES TO PAGES 169-178 8. James
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274 NOTES TO PAGES 194-201 57. Baze
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276 NOTES TO PAGES 219-227 5, 1996,
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278 NOTES TO PAGES 234-242 standing
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280 NOTES TO PAGES 255-260 8. The S
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282 BIBLIOGRAPHY the Pursuit of an
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Acknowledgments I stumbled onto the