Post coronary artery bypass graft surgery
Post coronary artery bypass graft surgery
Post coronary artery bypass graft surgery
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Improvement of cardiac function and tissue viability following<br />
expanded autologus marrow derived CD133 stem cell<br />
transplantation in patients with ischemic cardiomyopathy<br />
undergoing <strong>coronary</strong> <strong>bypass</strong> <strong>surgery</strong><br />
Ahmadi SH, Soleimani M, Sahebjam M, Ahmadbeigi N, Madani-Civi M,<br />
Fayazzadeh E, Najafi M, Karimi AA, Abbasi K, Marzban M, Shirzad M and<br />
Forouzannian KH<br />
Tehran Heart Center, Medical Sciences/University of Tehran, Tehran, Iran<br />
Abstract<br />
Background: Ischemic cardiomyopathy comprises nearly two thirds of cases with<br />
heart failure. Coronary revascularization through surgical <strong>bypass</strong> <strong>graft</strong>ing is now a days<br />
routinely performed to improve life quality of such patients. Simultaneous transplantation<br />
of stem cells in patients undergoing CABG has been described in some recent studies<br />
with promising results. In present randomized controlled trail, we investigated short term<br />
efficiency of stem cell transplantation on cardiac function as an adjuvant to conventional<br />
CABG technique in patients with congestive heart failure.<br />
Methods: After institutional review and university approval, 20 patients with ischemic<br />
cardiomyopathy (NYHA class III or IV) and low ejection fraction (
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