Post coronary artery bypass graft surgery

Clinical characteristics of women with premature coronary artery
disease requiring CABG compared with that of young men
Daryani YP and Daryani YP
Tehran Heart Center, Medical Sciences/University of Tehran, Tehran, Iran London, United Kingdom
Abstract
Background: Significant atherosclerotic CAD requiring CABG is uncommon in young
adults and it is even rarer in young females. Here we present and compare detail
characteristics of young female patients with premature CAD undergoing CABG with
that of young male patients in Iran.
Methods: In this study data from consecutive patients undergoing CABG only surgery
in a university affiliated tertiary referral centre in Tehran during twelve moths period
were obtained. Premature CAD was defined as development of atherosclerotic CAD
requiring bypass surgery before the age of 45 in men and before the age of 50 in women.
Their characteristics including main CAD risk factors (smoking, DM, hypertension,
hyperlipidemia, and family history), gender, BMI, creatinine levels, history of previous
MI, angina, heart failure, and prior cardio-vascular intervention were assessed and
compared. Standard criteria similar to those used by ACC/AHA were used to define the
patient's characteristics. However in this study a family history of CAD in first degree
relatives (both males and females) before the age of 55 was considered as positive.
Categorical data were compared using Chi-squared and continuous data were compared
using Student t test. P value