Risk Assessment – History and Future
Risk Assessment – History and Future
Risk Assessment – History and Future
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Postulated MOA for CHCl 3<br />
Oxidative<br />
CYP2E1<br />
Metabolism<br />
Chloroform<br />
Cl<br />
Cl<br />
C<br />
H<br />
Phosgene<br />
Cl<br />
Sustained cytoxicity<br />
Key events<br />
Regenerative cell proliferation<br />
Tumour development