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NEWS AT A GLANCE 05 | IMS MAGAZINE SUMMER 2012 GENOMIC MEDICINE
LETTER FROM THE EDITOR Letter from the Editor Nearly sixty years ago in a letter to Nature, Watson and Crick wrote: “We wish to suggest a structure for the salt of deoxyribose nucleic acid (DNA). This structure has novel features which are of considerable biological interest.” This first identification of DNA has paved the way for the field of medical genomics and, unknowingly to its discoverers at the time, has given promise of revolutionizing the diagnosis and treatment of many illnesses. This milestone should once again remind us that a scientific discovery can open up a multitude of opportunities for future research. In this issue of the IMS Magazine, we guide you through a detailed timeline of the evolution of molecular medicine—from the principles of heredity, to the first discovery of genomic DNA, to the identification of novel genes of various diseases. I hope it will inspire young researchers to think about the long-term implications of their research findings. Furthermore, with the help of our experts, we hope to educate you about some of the innovative research surrounding genomic medicine here at the IMS. We discuss next-generation sequencing technologies, human genetic variation, pharmacogenomics, epigenomics, and important ethical considerations of its translation to patient care. We hope that this will improve your understanding of personalized medicine and inform you about the ongoing, cutting-edge science at our institute. I also encourage you to take a look at our Viewpoint section and weigh in on our more contentious articles: we discuss the importance of understanding statistics in graduate education and controversies centered around publishing in journals with high impact factors. Be sure to also check out highlights from IMS Scientific Day, as well as our Close Up section featuring the winner of the Mel Silverman Mentorship Award, Dr. Gary Remington. Natalie Venier Editor-In-Chief Natalie Venier is a third year PhD Candidate at the Institute of Medical Science. She is currently studying prostate cancer chemoprevention at Sunnybrook Health Sciences Centre. To conclude, I would like to thank Dr. Allan Kaplan and the IMS department for their ongoing support, and congratulate our newest design team on their outstanding efforts in the production of this issue. I must acknowledge the phenomenal IMS Magazine team for their creativity and dedication, and our exceptional Managing Editor, Nina Bahl, whose dedication has been integral to our production. Lastly, I strongly encourage comments and feedback letters as we continue to aspire to bring you the best of the IMS. Enjoy! Photo by Paulina Rzeczkowska Natalie Venier Editor-In-Chief, IMS Magazine IMS MAGAZINE SUMMER 2012 GENOMIC MEDICINE | 06
Page 1: IMSMAGAZINE SUMMER THINK, LEARN, DI
Page 4 and 5: COMMENTARY Commentary On ‘A Recon
Page 8 and 9: NEWS AT A GLANCE NEWS&VIEWS JULY 28
Page 10 and 11: SPOTLIGHT Translational research an
Page 12 and 13: IMS SCIENTIFIC DAY HIGHLIGHT IMS SC
Page 14 and 15: FEATURE 13 | IMS MAGAZINE SUMMER 20
Page 16 and 17: FEATURE Ethics and Challenges of De
Page 18 and 19: FEATURE Psychiatric Pharmacogenetic
Page 20 and 21: FEATURE Spit for Science: A Populat
Page 22 and 23: FEATURE Epigenomics Beyond Genomic
Page 24 and 25: FEATURE SPOTLIGHT Advancing Genomic
Page 26 and 27: SPOTLIGHT Wenjun Xu The best of bot
Page 28 and 29: BOOK REVIEWS Book Reviews Excellent
Page 30 and 31: CLOSE UP Interview with Dr. Gary Re
Page 32 and 33: VIEWPOINT Publish and Perish Why sc
Page 34 and 35: VIEWPOINT A Numbers Game Why an art
Page 36 and 37: EXPERT OPINION Interactive proteomi
Page 38 and 39: FUTURE DIRECTIONS Dr. Gabriella Far
Page 40 and 41: RESEARCH HIGHLIGHT Genomic medicine
Page 42 and 43: PAST EVENTS PAST EVENTS This year
Page 44: READ IT ONLINE IMSMAGAZINE http://i

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