Herpes Vulvitis
Herpes Vulvitis
Herpes Vulvitis
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22/02/53<br />
Fibrovascular core, covered by sq epith.<br />
Paillomatosis<br />
Lack koilocytosis!<br />
Squamous papilloma<br />
Lichen sclerosus et atrophicus<br />
Clinical:<br />
• Whitened thinned epithelium<br />
• Symmetrical distribution<br />
• Labia minora shrinkage and agglutination in late stages.<br />
• Narrowed introitus or perianal stenosis (in children)<br />
• Occur in all ages grps, but common in postmenopause...<br />
• Unclear pathogenesis<br />
(genetic, autoimmunity, hormonal factors)<br />
• Insidious and progressive<br />
• Causes discomfort & predisposes to infection<br />
• Generally, not a precancerous condition<br />
BUT….a small proportion (about 1% to 4%) have been<br />
observed to develop carcinoma.<br />
1. Epithelial thinning/ hyperkeratosis<br />
2. Flattening rete ridges<br />
3. dermal edema and fibrosis<br />
Epithelial thinning with hyperkeratosis<br />
Hypertrophic vulvar dystrophy<br />
4. inflammatory cells<br />
Flattening of rete ridges<br />
Subepithelial or dermal edema and<br />
collagenous fibrous tissue change<br />
Chronic inflammatory cells in the areas<br />
4<br />
prgmea.com