Herpes Vulvitis

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22/02/53 Fibrovascular core, covered by sq epith. Paillomatosis Lack koilocytosis! Squamous papilloma Lichen sclerosus et atrophicus Clinical: • Whitened thinned epithelium • Symmetrical distribution • Labia minora shrinkage and agglutination in late stages. • Narrowed introitus or perianal stenosis (in children) • Occur in all ages grps, but common in postmenopause... • Unclear pathogenesis (genetic, autoimmunity, hormonal factors) • Insidious and progressive • Causes discomfort & predisposes to infection • Generally, not a precancerous condition BUT….a small proportion (about 1% to 4%) have been observed to develop carcinoma. 1. Epithelial thinning/ hyperkeratosis 2. Flattening rete ridges 3. dermal edema and fibrosis Epithelial thinning with hyperkeratosis Hypertrophic vulvar dystrophy 4. inflammatory cells Flattening of rete ridges Subepithelial or dermal edema and collagenous fibrous tissue change Chronic inflammatory cells in the areas 4 prgmea.com
22/02/53 hyperkeratosis... thickened keratin layer (secondary lichenification) expanded papillary dermis. **Biopsy is indicated in all lesions…… thickened epithelium, increased mitotic activity in both basal & prickle cell layers even those that are not so suspicious variable leukocytic infiltration of the dermis... squamous hyperplasia (previously called hyperplastic dystrophy) Lymphocytic inflammatory reaction Sclerotic or edematous change of dermoepidermal junction may present as: ulcer nodule macule pedunculated mass discharge bleed pain 5 prgmea.com
Page 1 and 2: 22/02/53 Clitoral hood Perineum Ra
Page 3: 22/02/53 may express in 3 forms 1.
Page 7 and 8: 22/02/53 VIN: type of lesion (N=73)
Page 9 and 10: 22/02/53 Cases should be classifie
Page 11 and 12: 22/02/53 • Uncommon variant of SC
Page 13 and 14: 22/02/53 * 1 st described in 1888,
Page 15 and 16: 22/02/53 DDx of vulvar intraepithel
Page 17 and 18: 22/02/53 Vaginal intraepithelial ne
Page 19 and 20: 22/02/53 Postoperative Spindle Cell
Page 21: 22/02/53 Aggressive angiomyxoma •

Herpes Vulvitis

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