Fitting Michaelis-Menten directly to substrate concentration data
Fitting Michaelis-Menten directly to substrate concentration data
Fitting Michaelis-Menten directly to substrate concentration data
- No tags were found...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Nested minimization[ n∑ ∫ {min min {s i −f (t i )} 2 +λ f ′ (t)− V }maxf (t) 2dt]{V max ,K m} βK m + f (t)i=1where f (t) = Φ(t)β, B-spline(Cao et al., Biometrics, 2011)