Cancer: A Brief Overview

The same effect can be obtained bymeans of any genomic event.Nature of event (type of change) is random;Choice of event (particular gene) is random;OncogenesTumorsuppressors-- Activating point mutations-- Translocation under strong promoter-- Amplification-- Overexpression-- Inactivating point mutations-- Promotor methylation-- Gross chromosomal deletions-- Underexpression