Cancer: A Brief Overview

What Is Telomerase?TEP1 may facilitateDNA bindingHolt et al, 2002P23 and HSP90are involved in assembly• RibonucleoproteinEnzyme• Reverse Transcriptaseenzyme• Adds TTAGGG repeatsto the 3’ end• Moves 3’ to 5’– In relation to telomeres• hTERT– Protein– Catalytic component• hTR– RNA– 451 bp