3 In the Drugs and Cosmetics Rules, 1945 - amam-ayurveda.org
3 In the Drugs and Cosmetics Rules, 1945 - amam-ayurveda.org
3 In the Drugs and Cosmetics Rules, 1945 - amam-ayurveda.org
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4210 30 30Low dose 6-106-10 2-3 2-3 15-3015-30<strong>In</strong>termediate 6- 6-10 2-3 2-3 15- 15-dose1030 30High dose 6- 6-10 2-3 2-3 15- 15-1030 304-6 4-64-6 4-64-6 4-62.0 Laboratory parameters to be included in toxicity studies.Haematological parameters• •• • Total • •• •HaemoglobinRBC Count HaematocritReticulocyte Count• • Total • •• •• •WBC CountDifferentialWBC CountPlatelet Count TerminalBoneMarrowExamination• • ESR • • General Blood Picture: A special mention of abnormal(Non-rodents<strong>and</strong> immature cells should be made.only)• • Coagulation Parameters (Non-rodents only): Bleeding Time, Coagulation Time,Prothrombin Time, Activated Partial Thromboplastin TimeUrinalysis Parameters• •• •• •• • 24-ColourAppearance SpecificGravityhour urinaryoutput• • • • • • • •
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