Issue 12 - amam-ayurveda.org

President’s Message 

May your Baisakhi be blessed 

with bounty of the season 

and a harvest of joy and 

prosperity 

Best Wishes!! 

Vaidya Devender Triguna 

Honored with Padma Shri and Padma Bhushan 

Volume 1, No.12, April –June’ 2012 

Index 

Contents Page 

From the Editor’s desk 2 

• Editorial Board 

• Executive Committee 

News Update 3 

• Union govt. draws up roadmap to 

promote ISM through NRHM 

• European Pharmacopoeia commences 

development of ‘Community 

Monographs’ for herbal remedies 

Pharamocopial Standards 5 

• Pushyanuga Churan 

• Patha 

• Jambu 

• Amra 

• Pashanbheda 

• Ativisha 

• Indrayava 

Clinical Study Report 11 

• Basant Kusmakar Ras 

Upcoming Events 15

Dear Members, 

From the Editor’s desk 

Ayurvedic medicines have been in use since ages. But today the whole 

world is looking at it, especially as a remedy for lifestyle ailments. 

Lot of research work has been done on ayurvedic herbs since its 

inception. Therefore there emerged a need for compilation of entire 

scientific development done so far post to the classical period. 

Realizing this need gap, a thought emerged and all the important work 

was compiled into a book form by Shri CP Khare and Dr. C K Katiyar 

along with Dr. VK Agrawal and Dr. Arun Gupta who aptly named 

the book as The Modern Ayurveda: Milestones Beyond the Classical 

Age. Mr. VC Burman (former chairman of Dabur India Limited) was 

the major inspiring factor behind conceptualizing this book. This 

book contains several topics that are essential to understand the surge 

of scientific work that is now being conducted on this age old system 

of medicine. 

The book enumerates more than 400 Ayurvedic herbs in a user friendly 

tabulated format including their botanical name, common Ayurvedic 

name, its family, chemical constituents, phytochemical markers, 

pharmacological actions, with their interactions and toxicity. 

For the evaluation of safety and efficacy of herbal medicine, this 

book explores current research methodologies adopted and makes us 

aware of the contemporary international regulatory status of herbal 

drugs in overseas. 

Today, a lot of universities have started academic courses; however 

there were no text books on Ayurveda containing chemical and 

pharmacological actions on herbs. 

Besides providing safety evaluation for the first time a book has been 

published by Francis and Taylor to fill the need gap. 

The writers of this book Mr. CP Khare has written many books on 

Indian medicinal herbs and Dr. C K Katiyar who is well known 

expert in ayurvedic research has published several research papers 

to his credit. This book is useful for students of Ayurveda in India 

and worldwide. The book will be equally helpful to researchers and 

academicians of Ayurveda. 

Dr. Manju Rakesh 

On behalf of full editorial board 

Disclaimer: Articles in the newsletter are written by independent individuals. News Clips of Upcoming 

Events, Govt. Notifications, Schemes have been taken from different sources. Their opinions do not 

necessarily reflect those of Info Ayurveda. They are put here for interest and reference only. None of the 

contributors, sponsors, administrators, or anyone else connected with Info Ayurveda in any way whatsoever 

shall be responsible for the appearance of any inaccurate information or for your use of the information 

contained in the newsletter. 

info Ayurveda, Volume 1, No.12, April-June’ 2012 

Patron 

Members of AMAM’s Management 

Committee 

Vaidya Brahaspati Dev Triguna 

Suresh Sharma 

Pradip Burman 

President 

Vaidya Devender Triguna 

Tel: 011-24354141 

Vice President 

Anurag Sharma 

Shri Baidyanath Ayurved Bhawan 

Ltd., (Jhansi) 

E-mail: anurag@baidyanathayurved.com 

Asad Mueed 

Hamdard (WAKF) Laboratories 

E-mail: amueed@hamdardindia.com 

Devendra Garg 

Dabur India Limited 

E-mail: gargd@dabur.com 

Ravi Prasad 

The Himalaya Drug Co. 

E-mail: ravi.prasad@himalayahealthcare.com 

Hon. Gen. Secretary 

Pradeep Multani 

Multani Pharmaceuticals Ltd. 

e-mail: chairman@multaniayurved.org 

Treasurer 

Tejinder Singh 


e-mail: singht@dabur.com 

Jt. Secretary 

Ajay Sharma 

Shri Baidyanath Ayurved Bhawan, 

New Delhi 

E-mail: ajdelhi@msn.com 

Arun Chauhan 

BACFO Pharmaceuticals (India) Ltd. 

E-mail: chauhanarun@akcgroup.com 

Dr. N.B. Brindavanam 


E-mail: baba@dabur.com 

M. J. Saxena 

Sanat Laboratories Ltd. 

E-mail: mjsaxena@anatproducts.co.in 

Members 

Vijay Grover 

Kamal Pharmacy, New Delhi 

E-mail: vijay@kamalpharmacy.com 

Pramod Sharma 

Shri Baidyanath Ayurved Bhawan 

Ltd. Patna 

E-mail: pramodsharma54@yahoo.com 



E-mail: rakeshm@dabur.com 

Amit Agarwal 

Natural Remedies 

E-mail: amit@naturalremedies.com 

Dr. Anantha Narayana D B, 

Ph.D., Consultant 

Email: dba.narayana@gmail.com 

Editorial Board: 

Chief Editor: 

Mr. Pradeep Multani 

Honorary General Secretary AMAM 

Chairman Multani Pharmaceutical Limited 

36-H Connaught place, New Delhi- 1 

Editor: 


Dabur India Limited, Plot No. 22, Site IV, 

Sahibabad - 201010, Ghaziabad (U.P.) 

Mr. Anurag Sharma, Executive Director 

Shri Baidyanath Ayurved Bhawan Pvt. Ltd. (Jhansi) 

B- 6/5, Safdarjung Enclave, New Delhi 

Mr. Asad Mueed, Director 

Hamdard (WAKF) Laboratories, Asaf Ali Road, New Delhi – 2 

Mr. Ajay Sharma, President 

Shri Baidyanath Ayurved Bhawan, Naini, 

28, Ishwar Nagar East, New Delhi – 65 

A Publication of: 

Association of Manufacturers of Ayurvedic Medicines 

Regd. Office: 22, Site –IV, Sahibabad, 

Ghaziabad - 201010 (UP), Tel: 0120 4378400, Fax: 0120 4376909 

Correspondence Address: H-36, Connaught Place, New Delhi-110001, 

Tel: 011-23350062, Fax: 011-23350063 

E-mail : amamindia@gmail.com website: www.amam-ayurveda.org 

2

Nandita Vijay, Bengaluru, Thursday, February 16, 2012, 08:00 Hrs [IST] 

The central government has drawn up an ambitious 

roadmap to promote Indian Systems of Medicine 

(ISM) like Ayurveda, Siddha, Unani, and therapies such 

as yoga and naturopathy through the National Rural 

Health Mission (NRHM). 

With yoga and naturopathy gaining worldwide 

acceptance, the government is now gearing up to address 

health issues across the population through these systems 

of medicine, stated S Gandhiselvan, minister of state for 

health and family welfare. 

“It is a foregone conclusion that yoga and naturopathy 

can prevent and cure various forms of ailments. In the last 

three decades, Yoga, in particular, has become popular 

all over the world as an effective disease management 

strategy. The government has decided to give special 

impetus to Yoga and Naturopathy so that the objectives 

of NRHM are met through the ISM,” he stated at the 

‘Arogya Expo 2012’ and the ‘International Conference 

on Yoga and Naturopathy’ (ICYN) Bengaluru held here 

from February 9-13. 

The broad policy support extended to the development 

of Ayush systems of medicine has ensured the organized 

development of all these six systems of healthcare based 

on their individual merits and strengths. 

The launch of NRHM has been significant for Ayush 

systems, as one of its objectives was to promote the 

effective provision of the healthcare to the masses. 


News update 

Union govt. draws up roadmap to promote 

ISM through NRHM 

Under NRHM, AYUSH doctors and facilities are being 

introduced in primary health centres and community 

health centres throughout the country. The availability 

of AYUSH facilities in PHCs and CHCs would ensure 

that the entire range of medical facilities would be 

available to the public and to the poor in particular. The 

main streaming of AYUSH in the healthcare system 

will have a significant impact on the health status of the 

people, stated the minister. 

“The NRHM is significant for ISM, as it is capable of 

meeting the objectives of India’s health requirements. 

The government intends to introduce ISM at the primary 

health centres and community health centres all over 

the country shortly. Yoga and naturopathy have been 

accepted for effective disease management because of 

their unique and holistic healing approaches. It is time 

we also took advantages of the same by introducing them 

through public health system,” the minister added. 

He pointed out that there were 6 lakh practitioners of 

ISM and homoeopathy in the country. However, that 

number was still insufficient to address the health issues 

plaguing the country. 

“The government is evolving a broad policy to promote 

ISM and Ayush colleges. At present, there are 488 Ayush 

colleges in the country. But the quality of education 

is a concern. We will make suitable suggestions after 

consulting experts in the field to improve the quality of 

education,” he explained. 

Courtesy : PHARMABIZ.com 

3

Nandita Vijay, Bengaluru, Friday, December 30, 2011, 08:00 Hrs [IST] 


European Pharmacopoeia commences 

development of ‘Community Monographs’ for 

European Pharmacopoeia and the European Medicine 

Agency have commenced the preparation of 

‘Community Monographs’ for herbal remedies. To begin 

with, the monographs will be made applicable for single 

herbs. 

The decision to create monographs is driven by 

the increasing shift in consumers opting for dietary 

supplements and nutraceuticals developed from herbs. 

The development of pharmacopoeia monographs would 

provide the much-needed information, stated Dr D B 

Anantha Narayana, leading scientist in herbal drugs and 

plant medicine. 

Even the government of India through the Indian 

Pharmacopoeia or Ayurveda Pharmacopoeia needs to 

take up this. It would be the best way to ensure India gets 

its prominent position in the global herbal map. In an age 

of growing consumption of herbal nutraceuticals, there 

is need for authentic information on products, its usage, 

quality, dosage forms and disease indications, he added. 

Pharmacopoeia monographs would serve not just for 

consumers but is important for physicians and pharmacists. 

US Pharmacopoeia (USP) is now primarily a regulatory 

quality specifications for all categories of drugs which 

can be extended to cover the ‘Dietary Supplements’. 

Although, mere presence of a herb in a Pharmacopoeia 

does not mean it is approved as a drug, yet its importance 

cannot be underestimated. Pharmacopoeia monographs 

provide a reference globally for quality specifications 

for the authentic identity, content, component quality. It 

is an assurance that the product sans contaminants like 

microbial, pesticides and heavy metals. The very mention 

of a herb in the pharmacopoeia monograph allows easy 

trade and reduces rejections in the global market. It is 

herbal remedies 

also an indication to ensure batch-to-batch consistency 

for researchers. While the herb with a monograph can 

promote future technology developments, it provides 

regulators a confidence on the history of usage and safety 

profiles in the large scale production of a product, said Dr 

Narayana. 

Globally, in the area of traditional knowledge based 

treatments, over 90 per cent of the products are botanical 

based. Despite the considerable discussions on need for 

standardization for herbal products, there has been a rise 

of use in herbal botanicals as supplements which do not 

come under the category of drugs. But the Pharmacopoeia 

experience coming handy has been largely to access the 

specifications of the herbs. 

Indian Pharmacopoeia 2010 [IP2010] has 89 monographs 

for herbs, processed herbs, including for extracts/oils, and 

herbal products. USP has over 180 monographs for herbs, 

powdered herbs, processed herbs including extracts, oils, 

and herbal products. British Pharmacopoeia (BP) has over 

50 monographs for herbs, powdered herbs, processed 

herbs including extracts, oils, and herbal products. 

European Pharmacopoeia (EP) has over 60 monographs 

for herbs, powdered herbs, processed herbs including 

extracts, oils, and herbal products. Pharmacopoeia of 

Republic of China [PRC] has over 180 monographs 

for herbs, powdered herbs, processed herbs including 

extracts, oils, and herbal products besides being the 

one that has quality specifications for large number of 

Traditional Chinese medicines (poly herbal). 

With international regulators insisting now insisting on 

authentic herbs with defined botanical identity India 

will need to look at building a ‘Minimum Therapeutic 

Guarantee’ basis and establish a natural window of few 

compounds and test for the compliance to the window, 

pointed out Dr Narayana. 

Courtesy: PHARMABIZ.com 

4

Pharmocopial Standards For Ayurvedic Formulations 

and Raw Materials 

PUSHYANUGA CHURNA 

(AFI PART – I, PG. 91-92.) 

ikBktECo;kseZ?;a f”kykHksna jlk¥tue~A 

vEc’Bdh ekspjl% leM~xk ineds”kje~AA46AA 

dV~Qya efjpa “kq.Bh e`}hdk jäpUnueAA47AA 

dV~oM~xoRldkuUrk /kkrdh e/kqdktZque~A 

iq’;s.kksÌR; rqY;kkfu “y{.kpw.kkZfu dkj;sr~AA48AA 

rkfu {kkSnzs.k la;ksT; ik;s;sÙk.M`ykEcqukA 

vl`Xnjkfrlkjs’kq jäa ;Ppksios”;rsAA49AA 

nks”kkxUrqd`rk ;s p ckykuka rka”p uk”k;sr~A 

;ksfunks’ka jtksnks’ka Üosra uhya lihrde~AA50AA 

L=h.kka “;kok:.k ;Pp rRizlã fuoÙkZ;srA 

pw.kZa iq’;kuqxa uke fgrek=s;iwftre~A 

vEc’Bk nf{k.ks [;krk x`à.kUr;U;s rq y{e.kke~AA51AA 

¼HkS’kT;jRukoyh] L=hjksxkf/kdj] 46&51½ 

1. Patha (Rt.) 1 Part 

2. Jambu (beeja majja) (Enm.) 1 Part 

3. Amra (beeja majja) (Enm.) 1 Part 

4. Shilabheda (Pashanabheda) (Rz.) 1 Part 

5. Rasanjana (Daruharidra) (St.Ext.) 1 Part 

6. Ambashthaki (patha) (Rt.) 1 Part 

7. Mocarasa (Exd.) 1 Part 

8. Samanga (Manjishtha) (Rt./Pl.) 1 Part 

9. Padma kesara (Adr.) 1 Part 

10. Vahika (Kumkuma) (Stl./Stg) 1 Part 

11. Ativisha (Rt.Tr.) 1 Part 

12. Musta (Rz.) 1 Part 

13. Bilva (St.Bk.) 1 Part 

14. Lodhra (St.Bk.) 1 Part 

15. Gairika 1 Part 

16. Katphala St.Bk.) 1 Part 

17. Marica (Fr.) 1 Part 

18. Shunthi (Rz.) 1 Part 

19. Mridvika (Dr.Fr.) 1 Part 

20. Rakta candana (Ht.Wd.) 1 Part 

21. Katvanga (Araluka) (St.Bk. 1 Part 

22. Vatsaka (Kutaja) (St.Bk.) 1 Part 

23. Ananta (Rt.) 1 Part 

24. Dhataki (Fl.) 1 Part 

25. Madhuka (Yashti) (Rt.) 1 Part 

26. Arjuna (St.Bk.) 1 Part 


Dose: 1 to 3 g 

Anupana: Honey and Tandulodaka 

Important Therapeutic Uses: Asrigdara, Shveta Pradara, Rajodosha 

PATHA (Root) 

(API Part –I, Vol. 1, Pg.92) 

Patha consists of roots of Cissampelos pareira Linn. (Fam. 

Menisperrnaceae), an extensively spreading, glabrous to softy pubescent, 

perennial climbing shrub with nodose stem, common in warm and dry 

regions of tropical and sub-tropical parts of India upto an altitude of about 

1500 m. 

SYNONYMS 

Sanskrit : Ambashthaki 

Assamese : Tuprilata 

Bengali : Patha, Akanadi 

English : Velvet leaf 

Gujrati : Venivel, Karedhium Kalipath, Karondhium, Karondium, 

Hindi : Patha, Padh, Akanadi 

Kannada : Pahadavela, Agalushunthi 

Kashmiri : Pad 

Malayalam : Patha 

Marathi : Pashadvel, Paharrel, Pahadavel, Padali 

Oriya : Kanabindhi, Patha 

Punjabi : Patha 

Tamil : Vatta tiruppi 

Telugu : Adivibankatiga, chiru boddi, Boddi tiga 

DESCRIPTION 

a) Macroscopic 

Roots, cylindrical, often tortuous, 1-1.5 cm in diameter, light brown to 

yellowish in colour, surface rough and at places rugged due to transverse 

wrinkles, cracks and fissures, fracture short and splintery, odour, faint 

aromatic, taste, bitter. 

b) Microscopic 

Transverse section of root shows, 6-10 layers of thin-walled, rectangular 

cork cells secondary cortex, 1-3 layered of oval to tangentially elongated 

5

cells, discontinuous ring consisting of 2-3 rows of stone cells and group 

of phloem fibres, stone cells variable in shape with simple pits, vascular 

strands as radiating strips usually 8-12 of xylem and phloem some reaching 

up to the centre, phloem consists of small strands of sieve elements and 

parenchyma just below the ring of stone cells, xylem consists of vessels, 

tracheids, fibres and xylem parenchyma, vessels and tracheids show simple 

pits on the walls, xylem parenchyma usually thick-walled and lignified 

but due to delignification patches of thin-walled parenchyma appear in 

the xylem region., medullary rays 1-3 seriate appear to be very wide at 

a number of places due to addition of delignified xylem parenchymatous 

cells, ray cells thin-walled, a few lignified and thick-walled while some 

show reticulate thickening, plenty of starch grains present in some of ray 

cells. 

Powder – Greyish-brown; under microscope shows group of cells, fibres 

and starch grains; crystals absent. 

IDENTITY, PURITY AND STRENGTH 

Foreign matter: Not more than 2 per cent, 

Total Ash: Not more than 7 per cent, 

Acid-insoluble ash: Not more than 1 per cent, 

Alcohol-soluble extractive: Not less than 11 per cent, 

Water-soluble extractive: Not less than 13 per cent, 

CONSTITUENTS - Alkaloids, saponin and quarternary ammonium 

bases, flavonol and sterol. 

PROPERTIES AND ACTION 

Rasa : Tikta, Katu 

Guna : Laghu, Tikshna 

Virya : Ushna 

Vipaka : Katu 

Karma : Tridoshashamana, Raktashodhaka, Vishaghna, Bhagnasand- 

hanakrit, Grahi, Stanyashodhana 

IMPORTANT FORMULATIONS - Pushyanuga Churna, Pradarantaka 

Lauha, Sarasvata Ghrita, Brihat Gangadhara Churna, Stanyashodhana 

Kashaya Churna 

THERAPEUTIC USES - Shularoga, Atisara, Kushtha, Kandu, Jvara, 

Chardi, Stanyadushti 

DOSE - 3-6 g of the drug in powder form. 

JAMBU (Seed) 

(API Part –I, Vol. II, Pg.54) 

Jambu consists of dried seeds of Syzygium cuminii (Linn.) Skeels Syn. 

Eugenia jambolana Lam.; E. cuminii Druce. (Fam. Myrtaceae); a large 


evergreen tree, attaining a height of 30 m and a girth of 3.6 m with a bole 

up to 15 m, found throughout India upto an altitude of 1,800 m. 

SYNONYMS 

Bengali : Badjam, Kalajam 

English : Jambul tree 

Gujrati : Gambu, Jamun 

Hindi : Jamuna 

Kannada : Nerale Beeja, Jambu Nerale 

Malayalam : Njaval 

Marathi : Jambul 

Oriya : Jam Kol, Jamu Kol 

Punjabi : Jaamun 

Tamil : Naval 

Telugu : Alla Nereduchettu, Neredu chettu 

Urdu : Jamun 

DESCRIPTION 

a) Macroscopic: 

2-5 seeds, compressed together into a mass resembling a single seed, 

the whole seed enclosed in a cream coloured, coriaceous covering, 

smooth, oval or roundish, 1 cm long, 1 cm wide, brownish-black; taste, 

astringent. 


Seed - Shows cotyledons consisting of single layered epidermis, mesophyll 

composed of isodiametric, thin-walled, parenchymatous cells fully packed 

with simple starch grains, oval, rounded measuring 7-28 μ in dia., a few 

schizogenous cavities are also found. 

Powder - Brown coloured; shows a few parenchymatous cells and 

numerous oval, rounded starch grains, measuring 7-28 μ in diameter. 






Water-soluble extractive: Not less than 15 per cent. 

T.L.C. 

T.L.C. of alcoholic extract of the drug on Silica gel ‘G’ plate using 

Toluene:Ethylaceate 

(90: 10) shows under U.V. light (366 nm) one fluorescent zone at Rf. 

0.30 (blue). On exposure to Iodine vapour four spots appear at Rf. 0.12, 

0.20, 0.30 and 0.95 (all yellow). On spraying with Vanillin-Sulphuric acid 

reagent and heating the plate for ten minutes at 105°C, three spots appear 

at Rf. 0.20, 0.30 and 0.95 and 0.95 (all violet). 

CONSTITUENTS 

Glycoside (Jamboline), Tannin, Ellagic acid and Gallic acid. 


Rasa : Madhura, Amla, Kashaya 

Guna : Guru, Ruksha 

Virya : Shita 

Vipaka : Katu 

Karma : Vatala, Pittahara, Kaphahara, Vishtambhi, Grahi 

IMPORTANT FORMULATIONS – Pushyanuga Churan 

THERAPEUTIC USES - Madhumeha, Udakameha 

DOSE - 3-6 g of the drug in powder form. 

6

AMRA (Seed) 

(API Part –I, Vol. III, Pg.7) 

Amra consists of dried seed of Mangifera indica Linn. (Fam. 

Anacardiaceae), a tree found wild or cultivated throughout the country. 

SYNONYMS 

Sanskrit : Amrabijamajja 

Bengali : Am 

English : Mango 

Gujrati : Aambaro, Ambanoo, Aambo, Keri 

Hindi : Aam 

Kannada : Amavina 

Malayalam : Manga 

Marathi : Aamba 

Oriya : Amkoili, Ambakoiti 

Tamil : Mangottai Paruppu, Maangottai 

Telugu : Mamidi-Jeedi 

Urdu : Aam 

DESCRIPTION 


Seed 3-4.5 cm long, 1.5-2.5 cm wide, ovoid, oblong covered with 

wrinkled integument, both outer and inner integument closely united, 

outer integument buff coloured, inner integument reddish-brown; taste, 

bitter and astringent. 


Seed shows outer integument consisting of tangentially elongated, irregular, 

thin walled, parenchymatous cells, with poorly developed conducting 

tissues of vessels showing spiral thickenings towards inner integument, 

inner integument consisting of slightly rectangular, wavy and large thinwalled 

parenchymatous cells; cotyledons 2, composed of isodiametric, 

parenchymatous cells fully packed with simple and compound starch 

grains; compound starch grains consisting of 2-6 components, each 

starch grain round to oval, measuring 2-28 μ in dia., a few conducting 

tissues with spiral vessels also found scattered in parenchymatous cells 

of cotyledons. 

Powder - Greyish-buff; shows reddish-orange coloured cells of integument, 

thin-walled, parenchymatous cells, simple and compound starch grains, 

consisting of 2-6 components, measuring 2-28 μ in diameter. 




Acid-insoluble ash: Not more than 0.5 per cent, 



T.L.C.- 

T.L.C. of the alcoholic extract on Silica gel ‘G’ plate using n-Butanol : 

Acetic acid: Water (4:1:5) shows under U.V. (366 nm) two fluorescent 


zones at Rf. 0.62 (yellowish) and 0.92 (blue). On exposure to Iodine 

vapour five spots appear at Rf. 0.07, 0.29, 0.62, 0.77 and 0.93 (all yellow). 

On spraying with 5% Methanolic-Sulphuric acid reagent and heating the 

plate for about ten minutes at 110°C five spots appear at Rf. 0.07 (grey), 

0.29 (grey), 0.62 (grey), 0.77 (brown) and 0.93 (brown). 

CONSTITUENTS - Tannins - Pyrogallotannins 


Rasa: Kashaya, Madhura 

Guna: Ruksha 

Virya: Shita 

Vipaka: Katu 

Karma : Samgrahi, Vatakara, Krimighna 

IMPORTANT FORMULATIONS - Pushyanuga Churna, Brihat 

Gangadhara Churna, Ashokarishta 

THERAPEUTIC USES - Atisara, Pravahika, Chardi, Daha, Tvagroga 

DOSE - 1-2 g of the drug in powder form 

PASHANABHEDA (Rhizome) 

(API Part –I, Vol. I, Pg.90) 

Pashanabheda consists of rhizomes of Bergenia ciliata (Haw.) Sternb., 

Syn. Bergenia ligulata (Wall.) Engl. (Fam. Saxifragaceae), a small 

perennial herb found throughout temperate Himalayas from Bhutan to 

Kashmir at an altitude between 2000-3000 m and in Khasia hills upto 

1200 m altitude. 

SYNONYMS 

Sanskrit: Ashmabhedaka, Shilabheda 

Assamese: Patharkuchi 

Bengali: Patharkuchi, Himasagara, Patrankur 

Gujrati: Pashanbheda, Pakhanbheda 

Hindi: Pakhanabheda, Silphara, Patharcua, Pakhanabhed, Silpbheda 

Kannada: Alepgaya, Pahanbhedi, Hittaga, Pasanaberu, Hittulaka 

Kashmiri : Pashanbhed 

Malayalam : Kallurvanchi, Kallurvanni, Kallorvanchi 

Marathi : Pashanbheda 

Oriya : Pasanbhedi, Pashanabheda 

Punjabi : Kachalu, Pashanbhed 

Tamil : Sirupilai 

Telugu : Kondapindi 

DESCRIPTION 


Rhizome, solid, barrel shaped, cylindrical, 1.5-3 cm long and 1-2 cm 

in diameter with small roots, ridges, furrows and root scars distinct, 

tranversely cut surface shows outer ring of brown coloured cork, short 

middle cortex, vascular bundles and large central pith, odour, aromatic, 

taste, astringent. 

7

) Microscopic 

Transverse section of rhizome shows cork divided into two zones, outer 

a few layers of slightly compressed and brown coloured cells, inner 

zone multilayered consisting of thin-walled tangentially elongatd and 

colourless cells, followed by a single layered cork cambium and 2-3 layers 

of secondary cortex composed of thick-walled, tangentially elongated, 

rectangular cells with intercellular spaces, some cells contain 

rosette crystals of calcium oxalate and simple starch grains cortex a narrowzone 

of parenchymatous cells containing a number of simple starch grains, 

most of cortical cells also contain large rosette crystals of calcium oxalate, 

endoderm is and pericycle absent. vascular bundles, arranged in a ring, 

collateral, conjoint and open, phloem tissues cornposed of sieve elements 

and parenchyma, in outer region found as compressed masses while in 

inner region intact. a number of rosette crystals of calcium oxalate also 

found as crystal fibres, cambium present as continuous ring composed of 

2-3 layers of thin walled, tangentially elongated cells, xylem consist of 

fibres, tracheids, vessels and parenchyma, with centre occupied by large 

pith composed of circular to oval, parenchymatous cells, varying in size 

and containing starch grains with crystals of calcium oxalate similar to 

those found in cortical region. 




Acid-insoluble ash: Not more than 0.5 per cent, 



CONSTITUENTS - Tannic acid, gallic acid and glucose 


Rasa: Tikta, Kashaya 

Guna: Laghu 

Virya: Shita 

Vipaka: Katu 

Karma: Ashmarighna, Bhedana, Vastishodhana, Mutravirecaniya 

IMPORTANT FORMULATIONS - Ashmarihara Kashaya Churna, 

Mutravirechaniya Kashaya Churna 

THERAPEUTIC USES - Meha, Mutrakricchra, Ashmari 

DOSE - 3-6 g of the drug in powder form 20-30 g of the drug for 

decoction. 

ATIVISHA (Root) 

(API Part –I, Vol.I, Pg.22) 

Ativisha consists of dried, tuberous roots of Aconitum heterophyllum 

Wall. ex. Royle (Fam, Ranunculaceae), a perennial herb, native of western 

Himalayas and found in Garhwal, Kumaon and Kashmir at altitude 

between 2,500-4,000 m. 


SYNONYMS 

Sanskrit: Aruna, Ghunapriya, Visa 

Assamese: Aatich 

Bengali: Ataicha 

English: Atis Root 

Gujrati: Ativishni Kali, Ativikhani Kali 

Hindi: Atis 

Kannada: Ativisha, Athihage 

Malayalam: Atividayam, Ativitayam 

Marathi: Ativisha 

Oriya: Atushi 

Punjabi: Atisa, Atees 

Tamil: Atividayam 

Urdu: Atees 

DESCRIPTION 


Roots, ovoid-conical, tapering downwards to a print, 2.0-7.5 cm long, 

0.4-1.6 cm or more thick at its upper extremity, gradually decreasing in 

thickness towards tapering end, externally light ash-grey, white or greybrown, 

while internally starch white, external surface wrinkled marked 

with scars of fallen rootlet and with a rosette of scaly rudimentary 

leaves on top: fracture, short, starchy, showing uniform white surface, 

marked towards centre by 4-7 concentrically arranged yellowish-brown 

dots, corresponding to end of fibro vascular bundles traversing root 

longitudinally taste, bitter with no tingling sensation. 


Transverse section of mature root shows, single layered epidermis 

consisting of light brown tabular cells rupturing on formation of cork, 

cork consists of 5-10 rows of tangentially elongated, thin-walled cells, 

cork cambium single layered consisting of tangentially elongated, thinwalled 

cells, cortex much wider consisting of tangentially elongated or 

rounded, thin-walled parenchymatous cells with intercellular spaces, 

cells fully packed with both simple as well as compound starch grains, 

compound starch gains composed of 2-4 components of spherical body, 

endodermis distinct composed of barrel shaped cells, elements of vascular 

bundles poorly developed, vascular bundles, arranged in a ring, interfascicular 

cambium present in form of a ring composed of few layered 

thin-walled cells, central core consisting of thin-walled parenchymatous 

cells, possessing starch grains similar to those found in cortical cells. 

Powder- Ash coloured to light brown, under microscope shows abundant 

simple and compound starch grains and parenchymatous cells. 







CONSTITUENTS - Alkaloids (atisine, dihydroatisine, hetisined and 

heteratisine). 


Rasa: Tikta, Katu 

Guna: Laghu, Ruksha 

Virya: Ushna 

Vipaka: Katu 

Karma: Dipana, Pachana, Sangrahika, Kaphapittahara 

IMPORTANT FORMULATIONS - Rodhrasava, Shiva Gutika, 

Lakshminarayana Rasa, Maha Vishagarbha Taila, Rasnairanadi 

Kvatha Churna, Sudarshana Churna, Panchatikta Guggulu Ghrita, 

Balachaturbhadrika Churna 

THERAPEUTIC USES - Jvara, Kasa, Chardi, Amatisara, Krimiroga 

DOSE - 0.6-2.0 g of the drug in powder form 

8

INDRAYAVA (Seed) 

(API Part I, Vol.III, pg.67-68) 

Indrayava consists of dried seeds of Holarrhena antidysenterica Wall. 

(Fam. Apocynaceae); a small to medium sized tree, found throughout 

India. 

SYNONYMS 

Sanskrit : Bhadra Yava, Kalinga, Sakra, Vatsaka 

Assamese : Dudhkuri 

Bengali : Kurchi 

English : Ester Tree, Conessi Seeds 

Gujrati : Kuda, Kudo 

Hindi : Indraju, Kurchi, Kuraiya 

Kannada : Kodasige Beeja 

Malayalam : Kutakappala 

Marathi : Kudayache Beej 

Oriya : Kurei, Keruan 

Punjabi : Indrajau, Kaurasakh, Kura 

Tamil : Kudasapalai 

Telugu : Kodisapala Vittulu, Palakodisa-Vittulu 

Urdu : Tukhm-e-Kurchi, Indarjao Talkh 

DESCRIPTION 


Seeds compressed, linear, or oblong, elongated, margins curved inside, 

one side convex and other side concave with a longitudinal striation; 1-2 

cm long, 0.2-0.3 cm thick, surface light yellowish- brown; odour, not 

distinct; taste, bitter. 


Seed shows 2-3 layered integument consisting of single layered, rounded, 

oval or radially elongated, thick-walled, reddish-brown parenchymatous 


cells, some of them elongate outwards forming small papillose structure, 

covered by a few unicellular, and uniseriate, multicellular types of 

trichomes; below this layer, 1 or 2 layers of small rounded or irregular 

cells, a few having single prismatic crystals of calcium oxalate, followed 

by a few layers of collapsed, brown coloured cells; endosperm 4-6 layered 

consisting of rounded, oval or polygonal, thin-walled, parenchymatous 

cells, containing aleurone grains; most ofthe cells also contain oil 

globules; embryo having conical radicle and two foliaceous, convoluted 

cotyledons consisting of single layered tabular epidermal cells towards 

dorsal side and rectangular cells towards ventral side, and externally 

covered with cuticle; rest of the cotyledon cells composed of rounded, 

oval or rectangular parenchymatous cells containing rosette crystals of 

calcium oxalate and oil globules. 

Powder - Light yellowish-brown; shows fragments of endosperm, pigment 

cells, oil globules, prismatic and rosette crystals of calcium oxalate. 



Total Ash; Not more than 8 per cent, 


Alcohol-soluble extractive: Not less than 12 per cent, 

T.L.C. 

T.L.C. of the alcoholic extract on Silica gel 'G' plate using Chloroform: 

Methanol (1:1) shows under U.V. (366 nm) four fluorescent zones at Rf. 

0.67, 0.72, 0.76 and 0.93 (all blue). On spraying with Dragendorff reagent 

followed by 5% Methanolic-Sulphuric acidreagent five spots appear at Rf. 

0.15, 0.28, 0.43, 0.59 and 0.67 (all orange). 

CONSTITUENTS - Alkaloids -Steroidal Alkaloid, Conessine etc., Fats, 

Tannin and resin. 


Rasa : Katu, Tikta 

Guna : Laghu, Ruksha 

Veerya : Shita 

Vipaka : Katu 

Karma : Deepana, Tridoshashamaka, Sangrahi 

IMPORTANT FORMULATIONS - Pancha Nimba Churan, Palasha 

Beejadi Churan, Laghu Gangadhardhara Churan, Krimi Kuthar 

Rasa, Piyushvalli Rasa, Jvaraghni Gutika, Siddha Praneshwar Rasa, 

Ahiphenasava 

THERAPEUTIC USES - Atisara, Kushtha, Jvaratisara, Krimi, Visarpa, 

Grahani, Raktatisara, Ela, Chardi, Tvagroga, Daha 

DOSE - 3-6 g (Churna) 

20-30 g (Decoction) 

Ancient Wisdom 

Among a man’s many good possessions, A good command of speech has no 

equal. Prosperity and ruin issue from the power of the tongue. Therefore, 

guard yourself against thoughtless speech. 

Tirukkural 65: 641-642 

9

FORMULATION COMPOSITION: 

1. Patha API Cissampelos pareira Rt. 1 part 

2. Jambu -bija majja API Syzygium cumini Enm. 1 part 

3. Amra-bija majja API Mangifera indica Enm. 1 part 

4. Shilabheda (Pashanabheda API) Bergenia ligulata Rz. 1 part 

5. Rasanjana API Berberis aristata Rt./St. Ext. 1 part 

6. Ambashthaki API Hibiscus sabdariffa Rt. 1 part 

7. Mocarasa (Shalmali) Salmalia malabarica Exd. 1 part 

8. Samanga (Lajjalu) API Mimosa pudica Rt./Pl. 1 part 

9. Padma kesara (Kamala) Nelumbo nucifera Adr. 1 part 

10. Vahlika (Kumkuma API) Crocus sativus Stl./Stg. 1 part 

11. Ativisha API Aconitum heterophyllum Rt. Tr. 1 part 

12. Musta API Cyperus rotundus Rf.Tr. 1 part 

13. Bilva API Aegle marmelos Rt./St.Bk. 1 part 

14. Lodhra API Symplocos racemosa St.Bk. 1 part 

15. Gairika (Shuddha) API Red ochre 1 part 

16. Katphala API Myrica nagi (M. esculenta) St. Bk. 1 part 

17. Marica API Piper nigrum Fr. 1 part 

18. Shunthi API Zingiber officinale Rz. 1 part 

19. Mridvika (Draksha API) Vitis vinifera Dr. Fr. 1 part 

20. Rakta candana API Pterocarpus santalinus Ht. Wd. 1 part 

21. Katvanga (Araluka API) Ailanthus excelsa St. Bk. 1 part 

22. Vatsaka (Kutaja API) Holarrhena antidysenterica St. Bk. 1 part 

23. Ananta (Shveta sariva API) Hemidesmus indicus Rt 1 part 

24. Dhataki API Woodfordia fruticosa Fl. 1 part 

25. Madhuka (Yasti API) Glycyrrhiza glabra Rt. 1 part 

26. Arjuna API Terminalia arjuna St. Bk. 1 part 

Method of preparation: 

Take all the ingredients of pharmacopoeial quality. 

Treat Gairika (No. 15) to prepare Shuddha Gairika (Appendix 6.2.7.2.), 

powder and pass through sieve number 85. Clean, dry and powder 

ingredients numbered 1 to 26 individually (except 15) and pass through 

sieve number 85. Weigh separately each powdered ingredient and mix 

together in specified ratio. Pass through sieve number 44 to prepare a 

homogeneous blend. 

Pack it in tightly closed containers to protect from light and moisture. 

Description: 

Reddish brown-coloured fine powder with a pungent odour and a bitter, 

sweet taste. The powder completely pass on through sieve number 44 and 

not less than 50 per cent pass on through sieve number 85. 

Identification 

Thin Layer Chromatography: 

Pharmocopial Standards For Pushyanuga Churna 

Extract 4 g of churna in alcohol (25 ml x 3) under reflux on a waterbath 

for 30 min filter, concentrate to 10 ml and carry out the thin layer 

chromatography. Apply 10 μl of the extract on TLC plate and develop the 

plate to a distance of 8 cm using toluene : ethyl acetate (5 : 2) as mobile 

phase. After development, allow the plate, to dry in air and examine under 

ultraviolet light (366 nm). It shows major spots at Rf 0.18 (blue), 0.73 


PUSHYANUGA CHURNA 

(API PART II, VOL.I, PG.55-56) 

DEFINITION:Pushyanuga Churan is a powder preparation made with the ingredients in the Formulation composition given below 

(fluorescent blue). Spray the plate with vanillin-sulphuric acid reagent 

followed by heating at 1100 for about 10 min and observe under visible 

light. The plate shows major spots at Rf 0.13 (grey), 0.27 (purple), 0.33 

(yellow), 0.53 (purple), 0.66 and 0.97 (both purple). 

Physico-chemical parameters: 

Loss on drying at 105 degree: Not more than 11 per cent, 

Total ash: Not more than 15 per cent, 

Acid-Insoluble ash: Not more than 4 per cent, 

Alcohol-soluble extractive: Not less than 12 per cent, 


pH (10% )aqueous solution: 5 to 6, 

Other requirements: 

Microbial limit: As in Appendix 2.4 of the book. 

Aflatoxin: As in Appendix 2.7 of the book. 

Storage: Store in a cool place in tightly closed containers, protected from 

light and moisture. 

Therapeutic uses: Asrigdhara (Menorrhagia), Shvetapradara 

(Leucorrhoea), Rajodosha (Menstrual disorder), Arsha (Piles), Yonidosha 

(disorders of female genital tract). 

Dose: 6 g daily in divided dose. 

Anupana: Milk or Tandulodaka. 

10

Observational Clinical Study On Basant Kusumarkar Ras 

In Diabetes & Diabetic Neuropathy 

INVESTIGATORS: 

Dr. Ashok Kumar Jain, 

Head, Department of Ayurveda, Panchkarma & Yoga 

and 

Dr. T. K. Das, 

Chief Neurologist, 

at 

SVS Marwari Hospital, Kolkata 

1. INTRODUCTION: 

Diabetes mellitus – generally termed as Madhumeha in Ayurvedic 

terminology, is a frequent clinical problem. The incidence of Diabetes has 

been on a constant rise during last few decades more in particular, in the 

developing countries like India. Insulin is a hormone produced by β islets 

of Langerhan’s cells in pancreas and this hormone is implicated to play a 

vital role in the metabolism of carbohydrates and utilization of glucose. 

Diabetes is characterized by a defective synthesis of insulin. 

Based on the mode of onset and the extent of damage to the insulin 

producing cells, diabetes is clinically classified into two types. The first 

type is termed as insulin dependent Diabetes mellitus [IDDM] and other is 

termed as Non-Insulin Dependent Diabetes Mellitus [NIDDM]. Modern 

therapeutic approaches have been fairly successful to handle the primary 

sequel of the problem, the hyperglycaemia. In case of IDDM, direct 

administration of Insulin and in case of NIDDM, hypoglycaemic agents 

have been successfully employed. 

Notwithstanding these developments, there are two major areas of 

concern. The first one being the incidence and distribution of diabetes. 

Of an estimated 80 million of diabetics, over 50m. belong to heavily 

populated, developing countries like India. The incidence also leans 

primarily, towards urban population. About 1.5% of urban population 

is diabetics as against a 0.8% rural population. There are countries/ 

communities with over 35% population being diabetics. Going by the 

upward trends in diabetic population the incidence appears to reach a 

phenomenally complex stage. 

The second important issue is the secondary sequel to diabetes. Many 

internal organs are likely to be effected due to a paradoxical glucose 

metabolism. Of all the diabetic maladies, diabetic neuropathy affects 

almost 30% cases in maturity on-set diabetes. In fact, the on-set of diabetes 

is often manifested by early changes of neuropathy like, tingling sensations 

in soles and palms, muscular pain in lower extremities, claudication etc. 

Thus, neuropathy is essentially identified together with diabetes mellitus. 

Unfortunately, the sequel of diabetes is mostly irreversible and there 

appears no practical approach to address them. 

On the other hand, Ayurveda has laid down a range of therapeutic measure 

to address various issues linked to diabetes or madhumeha. Many studies 

were conducted on a number of herbs mentioned in Ayurvedic literature 

with an objective to develop natural hypoglycaemic agents. The success 

in this direction has been very little for, most of the herbs failed to reduce 

blood sugar levels in the desired manner. The altered approach of these 

investigations was found to more effective, where, an ayurvedic medicinal 

plant is used as an adjuvant therapy to overcome drug resistance in 

diabetes. However, the efficacy of Ayurvedic drugs or formulations in 

different complications of diabetes was sparingly reported. 

Basant Kusumakar Ras in Diabetes: 

Basant Kusumakar Ras is a generic Ayurvedic, herbo-mineral formulation 


described in ancient Ayurvedic texts. As per Rasendrasar Sangraha, 

it contains Swarna Bhasma, Rajata Bhasma, Vanga Bhasma, Naga 

Bhasma, Kantaloha Bhasma, Abhraka Bhasma, Pravala Bhasma, and 

Mukta Bhasma. The blend is further processed in the extracts of 9 herbal 

ingredients and flavoured with Musk. 

Basant Kusumakar Ras is primarily, a Rasayana formulation but the 

text enumerates diabetes as one of its main therapeutic indication. The 

formulation is acclaimed to strengthen physiology as whole, to prevent 

loss of hair, premature graying of hair, to promote memory and fertility. 

Considering these descriptions, Ayurvedic physicians often recommend 

Basant Kusumakar Ras to improve/maintain the quality of life in diabetic 

patients. However, there have been no scientific reports to validate the 

acclaimed clinical usage of this formulation. 

Dabur Research centre have concluded experimental studies in 

collaboration with Department of Pharmacology, AIIMS – where Basant 

Kusumakar Ras was found to be having some improvement in blood sugar 

in Alloxan induced diabetic rats. This study thus succeeded to shed a little 

light on the role of formulation in diabetes mellitus. However, the role 

of Basant Kusumakar Ras in improving the quality of life during diabetic 

phase remains to be addressed. It is with this viewpoint; this observational 

clinical study was conducted at SVS Marwari Hospital, Kolkota from 

August 1998 to September. 2000 

2. OBJECTIVES OF THE STUDY: 

2.1. To ascertain the clinical efficacy of Basant Kusumakar Ras in 

controlling blood sugar as an adjuvant. 

2.2. To evaluate the role of Basant Kusumakar Ras in diabetic 

neuropathy. 

3. MATERIAL & METHODS: 

3.1. Inclusion Criteria: 

• Patients of both genders, suffering from clinically established diabetes 

for a period not less than 5 years duration and with a basal blood sugar 

levels of not less than 170 mg/dl were included in the study. 

• Both Insulin dependent [IDDM] and non-Insulin dependent [NIDDM] 

types of diabetics were included in the study. 

• Only those patients suffering from a marked degree of polyneuritis 

were included. 

3.2. Exclusion Criteria: 

• Pregnant women were excluded from the scope of this study. 

• Patients having renal impairment, hypertension and other forms of 

cardiovascular problems, liver afflictions were also excluded for the 

purpose of the study. 

3.3. Study Design: 

Open label prospective study 

3.4. Enrollment & Method of Study: 

The study was conducted at the SVS Marwari Hospital of Calcutta in 

11

collaboration with a Neurologist. Patients attending the Diabetes clinic 

at SVS Mawari Hospital meeting the above inclusion and exclusion 

criteria were enrolled in the study after recording baseline data. Basant 

Kusumakar Ras was administered at a dose of 125 mg. twice a day for a 

total period of 12 weeks. The patients were advised to continue the use 

of conventional therapy with Insulin or oral hypoglycaemic drugs as the 

case may be, to maintain the blood sugar levels. They were advised to visit 

follow-up clinic on day 15th, day 30th for a general observation related 

to dose adaptations. The efficacy follow-up was taken up, at the end of 

6 weeks and 12 weeks of therapy for recording subjective and objective 

data – which was subjected to statistical analysis at the end of study. The 

samples of Basant Kusumakar Ras for the study were provided by Dabur 

India limited. 

3.5. Parameters of evaluation: 

Efficacy evaluation was done based on both subjective and objective 

parameters for diabetes and diabetic neuropathy. 

Subjective parameters included and a general recording of symptoms 

related to diabetes. To assess the effect of BKR in polyneuritis, the 

following five cardinal symptoms were measured on a 0-3 grading scale: 

Pain } Where Gr. – 0 is complete absence 

Tingling } Gr. – 1 is Mild intensity 

Paraesthesia } Gr. – 2 is Moderate intensity 

Loss of Sensation [Los] } Gr. – 3 us Severe Intensity 

Impaired Pain Sensation [IPS] 

Such grading was done at baseline, at the end of 6 and 12 weeks of therapy 

with BKR. 

Objective parameters included estimation of blood sugar. Blood urea 

and Serum creatinine levels were estimated before during and the end 

of therapy to observe any possible effect of therapy on renal functions. 

Nerve Conduction Velocity [NCV] was measured in a group of 6 [25%] 

cases – to have a fair idea related to the efficacy of trial drug in diabetic 

neuropathy. 

3.6. Data Recording & Statistical Analysis: 

The study data was maintained in specially designed case record forms. 

For the purpose of statistical analysis, patients were divided among 

NIDDM [Group-A] and IDDM [Group-B]. ANOVA was applied to assess 

the inter-group variations and Tukey’s test was employed to analyze the 

intra-group variations. 

4. RESULTS: 

A total of 24 patients were included in the study. There were no dropout 

cases. Their age and sex distribution is shown in Table1. For the purpose 

of statistical analysis these 24 patients were divided into two groups based 

on the type of diabetes. Patient distribution among these two groups is 

shown in Table 2. 

Table 1: Demographic distribution of Study Population: 

Age Groups No. of Patients: 

Male Female Total 

30-45 years 6 2 8 

46-60 years 8 5 13 

61-75 years 2 1 3 

Grand Totals: 16 8 24 


Table 2: Distribution of patients between two types of Diabetes: 

Group(Type of Diabetes) No. of Patients: 

Male Female Total 

Group-A (NIDDM) 9 7 16 

Group-B (IDDM) 7 1 8 

Total 16 8 24 

4.1. Effect of Basant Kusumakar Ras on Blood Sugar Levels: 

While patients were receiving conventional therapy with oral hypoglycemic 

agents [in group-A] of Insulin [in Group-B], their blood sugar levels were 

found to be higher at baseline. On addition of Basant Kusumakar Ras 

at a dose of 125 mg. twice a day – there was a consistent drop. As seen 

from Table 3, BKR therapy was found to be significantly effective in 

controlling blood sugar levels and such therapeutic response was uniform 

in both NIDDM and IDDM groups. 

Table 3: Effect of Basant Kusumakar Ras on Blood Sugar Levels 

Group Mean Blood Sugar (SD±) P-Value S t a t i s t i c a l 

Significance 

Group-A 

(NIDDM) 

N=16 

Group-B 

( I D D M ) 

N=8 

Baseline After 6 

Wks 

2 3 9 . 3 8 

(43.82) 

2 3 9 . 1 3 

(55.32) 

175.25 

(43.82) 

184.00 

(22.60) 

A f t e r 

12 Wks 

163.75 

(37.35) 

194.37 

(55.38) 

Table 4: Effect of Basant Kusumakar Ras on Pain Score: 

Group Mean Blood Sugar (SD±) P-Value S t a t i s t i c a l 

Significance 

Group-A 

(NIDDM) 

N=16 

Group-B 

( I D D M ) 

N=8 

Baseline After 6 

Wks 

1 . 9 4 

(0.77) 

2 . 2 5 

(0.71) 

1 . 8 1 

(0.66) 

2 . 1 3 

(0.64) 

A f t e r 

12 Wks 

1 . 1 9 

(0.54) 

1 . 7 5 

(0.71) 


4.3. Effect of Basant Kusumakar Ras on Nerve Conduction Velocity: 

Nerve conduction velocity was done in 25% of enrolled cases before and 

after 12 weeks of therapy. No significant changes were noted after therapy 

with Basant Kusumakar Ras. 

4.4. Effect of Renal Function Tests: 

To note any adverse effects of Basant Kusumakar Ras therapy, renal 

function tests were carried out on all patients before, during and after 

therapy. There were no significant differences in these values – suggesting 

that, the metallic ingredients don’t exhibit any renal toxicity. 

5. DISCUSSION & CONCLUSION: 

Basant Kusumakara Ras (BKR) is described in Ayurvedic literature, to work 

as Rasayana. Based on its composition and other relevant descriptions, the 

formulation is being used by Ayurvedic fraternity, as a specific Naimittika 

Rasayana in diabetic population. The present observational clinical study 

was aimed to understand the role of Basant Kusumakar Ras in diabetes 

and diabetic neuropathy. Going by the therapeutic attributes of the 

formulation and its ingredients, it was presumed that, BKR might play 

some significant role in normalizing the neuropathic changes in diabetic 

patients. However, the results are not in full favour of this presumption as 

Basant Kusumakar Ras have shown some improvement in pain score and 

tingling score only and not in parasthaesia score, loss of sensation score 

and impaired pain sensation scores. Basant Kusumakar Ras was found 

to effective as an adjuvant therapy along with conventional therapy of 

Insulin and oral hypoglycemic drugs in controlling blood sugar levels in 

both NIDDM and IDDM patients. This observation justifies the current 

trends of its usage as naimittika rasayana for diabetic population. No 

specific safety concerns were noted for the use of Basant Kusumakar Ras 

in diabetic population. 

6. ACKNOWLEDGEMENT 

The investigators are thankful to Dr C.K. Katiyar from Dabur India 

Limited for providing the study drug samples and extending the financial 

help for the conduct of the study. 

info 

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Note: Please enclose the CD of the Artwork alongwith Bank Draft/cheque in favour of “Association of Manufacturers of Ayurvedic Medicines” 

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7. REFERENCES: 

1. Shah, SN & Tripathi, BB [1992]; in chapter on Diabetes mellitus, API 

Textbook of Medicine, edited by Sainani, GS, Association of Physicians 

of India, Bombay, 4th ed., pp-204-205. 

2. Ritchie AC [ed.] [1990]: In Boyd’s Textbook of Pathology, Lee & 

Febiger, Indian Edition published by KM Verghese & Co, Bombay, vol.- 

II, pp-1780. 

3. Rahman, A & Zaman, K [1989]: Plants with Hypoglycaemic Activity, 

Jour, Ethnopharmacol., vo.26, pp-1-55. 

4. Mukherjee, PK, Banerjee, SN & Jain, AK [1995]: Clinical studies on 

Neem Capsules as an Adjuvant therapy in resistant cases of NIDDM. Data 

on files of Dabur Research Foundation. 

5. Tripathi. ID [1987]: in Trans. Of & Rasavidyotini commentary to 

Rasendrasarasangraha of Gopalabhatta, published by Chaukhambha 

Orientalia, Varanasi. 

6. Gupta, S K [1999]: effect of Basant Kusumakar Ras on Alloxan 

Induced diabetes in experimental Animals. Data on files of Dabur Research 

Foundation. 

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14

Herbal International Summit cum Expo on 

Medicinal & Aromatic Products, Spices & 

finished Products 


UPCOMING EVENTS 

Date: 14-APR-12 to 15-APR-12 

Herbal International Summit cum Expo on Medicinal & Aromatic Products, 

Spices & finished Products is a mega event showcase continental, regional 

& local competence in this industry & to promote worldwide upcoming 

business of herbals, spices and finished products. More than 100 prominent 

companies to participate in this event including foreign companies. 

Venue: NSIC Exhibition Complex, New Delhi, Delhi, India 

Eso-Natura Fair lindau 

Date: 17-AUG-12 to 19-AUG-12 

Eso-Natura Fair lindau is going to be great opportunity to discover the 

field of natural and supernatural medicine. The event will provide a perfect 

chance to the visitors to explore the world of mysticism and healing. The 

visitors will be able to find a wide range of health products and services at 

the fair. The event will also help them to learn new ideas. The Eso-Natura 

Fair Olten is being seen as a place which will provide a platform to the 

exhibitors to showcase their products and to not only increase their profit 

but also increase their business in new areas. 

Venue: TBA, Lindau, Bayern, Germany 

Natural Products Expo 

Date: 23-AUG-12 to 25-AUG-12 

Asia is the largest exhibition on Natural Products in Asia which will be 

held between 23-25 Aug 2012 at Hong Kong Convention & Exhibition 

Centre (HKCEC). The trade show is expected to attract record number of 

exhibitors and attendees, reflecting the explosive growth of the natural, 

organic, and health sector across the region. 

Venue: Hong Kong Convention & Exhibition Centre, Hong Kong, China 

(Hong Kong S.A.R.) 

SANA 

Date: 09-SEP-12 to 12-SEP-12 

SANA Expo, the International Exhibition of Natural Products - 

NUTRITION, HEALTH, ENVIRONMENT is the main event for the 

whole natural world. Since 16 years, Sana has been acting as a diffuser of a 

new culture and nowadays represents the reference point where to discuss 

and to plan the future for a quality life, with respect to environment. 

Venue: Bologna Fair Centre, Bologna, Emilia-Romagna, Italy 

courtsey: biztradeshows.com 

15

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B. Affiliated membership for Organization/Federations Rs. 10000/year 

Published by: 


Regd. Office: 22 Site –IV, Sahibabad, Ghaziabad - 201010 (UP), Tel: 0120, 4378400, Fax: 0120 4376909 

Correspondence Address: H-36, Connaught Place, New Delhi-110001, Tel: 011-23350062, Fax: 011-23350063 

E-mail : amamindia@gmail.com website: www.amam-ayurveda.org 

Approved / Rejected 

Pradeep Multani 

General Secretary 

may be enlarged and xeroxed

Issue 12 - amam-ayurveda.org

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