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Download a PDF of the 2012 Annual Report - Black Dog Institute

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Determining melancholic from non-melancholicdepression – This study aimed to separatefeatures that are different for ‘melancholic’ and ‘nonmelancholic’depression. It is suggested that ‘melancholic’depression (about 10 per cent <strong>of</strong> depressivedisorder) is a more biological illness and that <strong>the</strong> bulk<strong>of</strong> depressive disorder can be categorised as ‘nonmelancholic’,with <strong>the</strong> latter more closely associatedwith stress and personality factors. The Sydney MelancholiaPrototype Index developed by <strong>the</strong> researchersfound that ‘non-melancholic’ participants in <strong>the</strong>study had more anxiety disorders, a higher number <strong>of</strong>stressors and were more likely to have a personalitystyle that could predispose <strong>the</strong>m to non-melancholicdepression. Clinician ratings <strong>of</strong> patients were foundto be more accurate than ratings made by patients <strong>of</strong><strong>the</strong>ir own mood state.Implications <strong>of</strong> genetic tests for psychiatricillness – It is now possible to link a person’s genetic‘markers’ to <strong>the</strong>ir risk <strong>of</strong> developing a particulardisease and to sell such tests direct to <strong>the</strong> consumer.Since <strong>the</strong> information may influence life-changinghealth decisions, it is very important to ensure that<strong>the</strong>re is sound evidence to support <strong>the</strong> use <strong>of</strong> any particulargenetic test. Advantages <strong>of</strong> such tests are thatearly protection such as medication and <strong>the</strong>rapies canbe implemented, hopefully lowering risk, and somegenetic tests can also predict medication response.Disadvantages include that such tests can increasera<strong>the</strong>r than diminish stigma, and cause unnecessarydistress and discrimination in instances where <strong>the</strong> illness/conditionnever develops.BLACK DOG <strong>2012</strong>17

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