Lipid nanocapsules: a tool for improving - AAPS

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Mechanistic studypswc2010 E.Roger et al. Nanomedicine 5(2) (2010) 287-306
LNC uptake - Identification of receptor-mediatedendocytosis pathwaysMethylβCD/Lovastatin: ✖lipid raftsFilipin: ✖caveolae-mediat. endocytosisChlorpromazin: ✖clathrin-mediat.endocytosisFilipin has the most importantimpact on LNC uptake but theother inhibitors also decrease it.intracellular trafficking?pswc2010
Page 6 and 7: WaterOilConductivityPhase Inversion
Page 8 and 9: Routes of administrationPulmonaryro
Page 10 and 11: First PK Study with PTX-LNCS. Pelti
Page 12 and 13: Development strategy of an oralLNC
Page 14 and 15: Methodology used with Caco-2 cells
Page 18 and 19: PTX-LNCs : where are we ?‣ Enhanc
Page 20 and 21: Sn38-LNC‣ Poorly soluble anticanc
Page 22 and 23: Permeability across Caco-2 cellsFre
Page 24 and 25: Nano-encapsulation of Sn 38‣ Sn 3
Page 26 and 27: Perspectives‣ Assessment on cell
Page 28 and 29: LNC transport through the Caco-2 mo

Lipid nanocapsules: a tool for improving - AAPS

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