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DISCOVERY XT brochure - Ventana Medical Systems

DISCOVERY XT brochure - Ventana Medical Systems

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<strong>DISCOVERY</strong> ®<strong>XT</strong>Biomarker PlatformAutomated IHC, ISH, and Microarrayslide processing system


Staining ModuleThe staining module creates an optimized environmentfor the automated preparation and processing of IHC,ISH, FISH, tissue and DNA microarray applications.Automated Fluidics ModuleThe automated fluidics module houses bulk solutionsspecifically formulated to enhance kinetics and resultreproducibility. On-board bulk fluid capacity to processup to 90 slides. Easy “no drip” loading prevents spillageThermoFlex Pad slide platform provides individualtemperature control for precise heating of up to 30 slides.and waste. Seven color coded and numbered bottlesensure accurate replenishment. Front panel accessprovides convenient replacement and servicing.Reagent Carousel capacity of up to 35 reagentdispensers.Waste ModuleReagent Dispensers individually bar-coded, eliminatingthe time and error associated with manual data entry.Two easy-empty containers with independent levelsensing. Waste capacity for walk-away operation of up to90 slides.1 800 227 2155 www.ventanamed.com


Accelerate Your Discoveryand development decisions<strong>DISCOVERY</strong> ® <strong>XT</strong> Biomarker PlatformThe new <strong>DISCOVERY</strong> <strong>XT</strong> System brings unprecedentedreproducibility and productivity through automationto immunohistochemistry (IHC), in situ hybridization(ISH) and microarray slide preparation and processing.Use the flexible <strong>DISCOVERY</strong> <strong>XT</strong> platform to acceleratethe discovery of new targets and biomarkers, speedassay development and target validation, and quicklydetermine the toxicity of new drug candidates in thepreclinical phase.Optimal FlexibilityProcess IHC, ISH, TMA or DNA microarray samplesindependently or simultaneously. Develop protocols withflexible options to design matrix experiments (up to 30slides). Automate any one, or all slide preparation stepsincluding baking, deparaffinization, cell conditioningand staining.Superior ReproducibilityMinimize experiment repeats with the automation of allslide processing steps - from baking through staining.The <strong>DISCOVERY</strong> <strong>XT</strong> biomarker platform isthe next generation of flexible automationfor molecular pathology, genomics, andproteomics research.Enhance slide-to-slide and run-to run reproducibilitywith ready-to-use, automation optimized reagents<strong>Ventana</strong> <strong>Medical</strong> <strong>Systems</strong>a member of the Roche Group


Optimized KineticsProprietary <strong>DISCOVERY</strong> <strong>XT</strong> automation technology is responsiblefor the unprecedented reproducibility of experimental IHC, ISH,TMA and DNA microarray application data.Liquid CoverslipSlide-Specific LabelAir Vortex MixingTissueAqueous LayerThermoFlex PadThermoFlex Pad: individual slideheaters provide highly precise heatingacross the entire surface of each slide,ranging from 37º C to 100º C.Air-Vortex Mixers: blend theaqueous layer under the LiquidCoverslip, mixing reagents andensuring uniform reaction kineticsacross the entire surface of the slide.Multi-spense: provides precisedilutions of critical reagents therebyenhancing assay kinetics andreproducibility.Liquid Coverslip: creates a reactionchamber on the surface of each slidecontrolling evaporation and protectingtissue integrity.Jet Drain: removes aqueous solutionsto optimize probe concentration forISH applications.Dual Rinse: reduces excessbackground by efficiently removingexcess reagents, ensuring consistentand reproducible slide staining.1 800 227 2155 www.ventanamed.com

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