Emerging Markets for Microfluidic Applications - I-Micronews
Emerging Markets for Microfluidic Applications - I-Micronews
Emerging Markets for Microfluidic Applications - I-Micronews
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<strong>Emerging</strong> <strong>Markets</strong> <strong>for</strong><br />
<strong>Microfluidic</strong> <strong>Applications</strong><br />
(EMMA 2011)<br />
Report Sample<br />
45 rue Sainte Geneviève, F-69006 Lyon, France<br />
Tel : +33 472 83 01 80 - Fax : +33 472 83 01 83<br />
Web: http://www.yole.fr
Table of content<br />
1 – EXECUTIVE SUMMARY<br />
2 – INTRODUCTION<br />
3 – MICROFLUIDICS MARKET 2011-<br />
2016<br />
• Market geographical distribution<br />
• Impact of microfluidics<br />
• <strong>Microfluidic</strong> applications<br />
• <strong>Microfluidic</strong> components market value<br />
and <strong>for</strong>ecast<br />
• Compound Annual Growth Rates<br />
2008-<br />
2010 and 2011-2016<br />
4 – WHAT HAPPENED SINCE 2009?<br />
• <strong>Microfluidic</strong>s, a dynamic market<br />
• <strong>Microfluidic</strong> Patents 2009-2011<br />
• Market data versus EMMA2009<br />
<strong>for</strong>ecasts<br />
© 2011 • 2<br />
5 – MICROFLUIDIC APPLICATIONS<br />
• General Dispensing<br />
• Drug Delivery<br />
• Accurate Dispensing<br />
• Analytical Devices<br />
• Clinical and veterinary diagnostics<br />
• Point Of Care testing<br />
• Industrial and environmental testing<br />
• Pharmaceutical and life science<br />
• Microreaction technology<br />
6 – MICROFLUIDIC TECHNOLOGIES<br />
7 – MICROFLUIDIC SUPPLY CHAIN<br />
8 – MICROFLUIDIC VALUE CHAIN<br />
9 – SUMMARY AND CONCLUSIONS<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.
EMMA 2011: Scope<br />
© 2011 • 3<br />
<strong>Microfluidic</strong>s<br />
Technologies<br />
<strong>Microfluidic</strong>s<br />
<strong>Applications</strong><br />
Market data<br />
& Forecasts<br />
EMMA<br />
2011<br />
<strong>Microfluidic</strong>s<br />
Supply<br />
Chain<br />
What happen<br />
since 2009?<br />
Many device<br />
examples <strong>for</strong><br />
each<br />
application<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.
<strong>Microfluidic</strong>s Component Market<br />
Three assumptions <strong>for</strong> the future<br />
<strong>Microfluidic</strong> Devices market in M$<br />
© 2011 • 4<br />
5000<br />
4500<br />
4000<br />
3500<br />
3000<br />
2500<br />
2000<br />
1500<br />
1000<br />
500<br />
0<br />
<strong>Microfluidic</strong> Devices market in M$<br />
2010 2011 2012 2013 2014 2015 2016<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Micro Reaction Technology<br />
Drug delivery (inhalers,<br />
micropumps, microneedles)<br />
Industrial and environmental<br />
Analytical devices<br />
Pharmaceutical and life science<br />
research<br />
Point of Care diagnostics<br />
clinical & veterinary diagnostics<br />
Total <strong>for</strong>ecast<br />
Optimistic Forecast<br />
Pessimistic Forecast
Market data versus EMMA 2009 <strong>for</strong>ecasts<br />
• The graph below shows the microfluidics device market, as predicted in the EMMA<br />
2009 and the actual data obtained from reported sales of the top 150 players.<br />
• <strong>Microfluidic</strong> device market has grown less than predicted in our last report due to<br />
the fact that the segment Point of Care has not taken off as expected.<br />
© 2011 • 5<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.
Market data versus EMMA 2009 <strong>for</strong>ecasts<br />
(M$)<br />
50<br />
45<br />
40<br />
35<br />
30<br />
25<br />
© 2011 • 6<br />
Industrial and environmental<br />
20<br />
2008 2009 2010<br />
Industrial &<br />
environment<br />
applications,<br />
including Energy<br />
- EMMA 2009<br />
Industrial &<br />
environment<br />
applications,<br />
including Energy<br />
- Real<br />
The industrial and environmental segment has<br />
experienced a strong growth<br />
In Yole Developpement opinion this growth can be<br />
explained by the fact that many hidden technologies in<br />
development came on the market and generated sales.<br />
In addition, many technologies originally developed <strong>for</strong><br />
the POC market found an application in the<br />
environmental and agro-food applications.<br />
(M$)<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
190<br />
170<br />
150<br />
130<br />
Drug Delivery<br />
110<br />
2008 2009 2010<br />
Drug Delivery -<br />
EMMA 2009<br />
Drug Delivery -<br />
Real<br />
<strong>Microfluidic</strong> technologies <strong>for</strong> drug delivery have<br />
experienced a sustained growth with a CAGR<br />
of 21% during the period 2008-2010.<br />
<strong>Microfluidic</strong> technologies seem to be important<br />
tools in order to improve the efficacy and<br />
reduce side effects of the treatment.<br />
The growth observed can be principally<br />
accounted to the market success of the inhaler<br />
technology of Boehringer Ingelheim (Respimat)
<strong>Microfluidic</strong>s technologies & applications<br />
Technologies<br />
Legend:<br />
© 2011 • 7<br />
Dispensing<br />
Micro analysis devices<br />
Chemical & biological<br />
Synthesis<br />
<strong>Applications</strong><br />
Medical<br />
applications<br />
Drug Delivery<br />
Inhalers<br />
Microneedles<br />
Analytical<br />
Device<br />
Dispensing, Spotting<br />
Analyses<br />
= <strong>Microfluidic</strong>s chips<br />
In Vitro Diagnostic applications<br />
Clinical & Veterinary<br />
Diagnostics<br />
Cartridges <strong>for</strong><br />
clinical and<br />
veterinary<br />
diagnostics<br />
Point Of Care<br />
Micropumps, Microvalves<br />
POC<br />
Intensive<br />
care, doctor<br />
office, near<br />
patient,…<br />
Industrial &<br />
Environment<br />
Testing<br />
Identification<br />
of pathogens<br />
(Agro Food,<br />
Water analysis)<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Research & Production<br />
applications<br />
Pharmaceutical<br />
research<br />
Dispensing,<br />
Spotting<br />
Genomics<br />
Proteomics<br />
Cell based<br />
assays<br />
Microreaction<br />
Micro Reaction<br />
- Research units<br />
- Pilot production<br />
units
Chips / <strong>Applications</strong> in IVD Diagnosis<br />
Type of detection<br />
on chip<br />
<strong>Applications</strong><br />
© 2011 • 8<br />
Chemicals<br />
detection<br />
Blood gas<br />
analysis<br />
Immunoassays<br />
detection<br />
• Serodiagnostic<br />
• Fast and low<br />
cost Pathogen<br />
detection<br />
(bacteria, virus)<br />
• Pathogen<br />
identification<br />
(strains,<br />
serogroup)<br />
In Vitro Diagnosis<br />
Molecular<br />
detection<br />
• Accurate<br />
pathogen<br />
detection and<br />
identification<br />
• Typing<br />
• Pathogen<br />
quantification<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Cytometry<br />
detection<br />
• Complete Blood<br />
Count (CBC)<br />
• Detection and<br />
analysis of<br />
microscopic<br />
particles such<br />
as bacteria and<br />
animal cells
Drug Delivery and Infusion Devices<br />
�µneedels<br />
© 2011 • 9<br />
Boehringer<br />
MicroParts<br />
Respimat®<br />
Wearable Electronic<br />
Disposable Drug delivery<br />
Birch Point Medical Inc.<br />
WEDD<br />
R&D<br />
�Smart Patches<br />
� Needle free injection<br />
Ceramic microneedles<br />
R&D<br />
Commercially<br />
available $<br />
Commercially<br />
available $$$<br />
� Inhalers<br />
Inhalation and<br />
spray delivery<br />
Transdermal<br />
Injection<br />
devices<br />
ZA Medical<br />
Medspray<br />
Active drug<br />
delivery<br />
systems<br />
The Intellidrug tooth implant<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Roche - Disetronic<br />
Panomat®<br />
Microdosage pumps<br />
� Infusion pumps<br />
� Implantable pumps<br />
� Smart pills<br />
ChipRx<br />
Commercially<br />
available $$$<br />
R&D<br />
R&D<br />
Debiotech micropump
Materials distribution<br />
2010<br />
© 2011 • 10<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.
Silicon <strong>Microfluidic</strong>s supply chain & players<br />
© 2011 • 11<br />
Design Prototype Volume Integration and distribution<br />
<strong>Microfluidic</strong>s<br />
players<br />
CEA Leti, DTU, IMEC,<br />
FZK,ITRI, VTT, Draper<br />
Lab…<br />
IDMs<br />
STM, Sharp, IBM, NXP, Philips, TEL<br />
MEMS Foundries<br />
Silex, Dalsa, Colibrys, IMT, Lionix, C2V, SVTC, Olivetti…<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Integrators<br />
Agilent Biomerieux Veredus<br />
Mobidiag<br />
Life Technology,<br />
Pacific Bioscience<br />
Silicon Biosystems<br />
...
Yole activities in <strong>Microfluidic</strong>s<br />
© 2011 • 12<br />
Media business<br />
News feed / Magazines /<br />
Webcasts<br />
Market<br />
Research<br />
Reports &<br />
database<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.<br />
Consulting<br />
services<br />
Market research,<br />
Technology & Strategy<br />
www.yole.fr
<strong>Microfluidic</strong>s reports from YOLE<br />
© 2011 • 13<br />
EMMA 2011 September 2011 Copyrights © Yole Développement SA. All rights reserved.