CMA-Microdialysis.pdf - somapharm.ch

Microdialysis for Basic ResearchProbesMicrodialysis Probesoverview9ALL CMA MICRODIALYSIS PROBES have the same concentric construction except the linear probes. An inner cannula leads the perfusion fluid from theinlet to the tip of the probe where it comes in contact with the semi-permeable membrane. The fluid then continues up through the outer shaft on its way tothe outlet. All metal parts are treated to prevent oxidation of labile compounds in the perfusate. A variety of probe types, sizes, and membranes are describedover the next few pages. Probes are delivered in vacuum-sealed packages, 3 pc/pkg, or 4 pc/pkg, and each probe is guaranteed for single use. Flexibleprobes are packaged with introducers and split tubing guides. The linear probes consist of a tubing in which the middle part has a window with a membrane,where microdialysis takes place. Complete instructions are included in each package.CMA 12 + guide cannulaCMA 11 + guide cannulaCMA 7 + guide cannulaOptimized for CNS useIdeal for chronic implantationRange of different lengthsAvailable membranes:PAES, 20kD MWCOPES, 100kD MWCOMembrane lengths - 1, 2, 3 or 4 mmMembrane diameter - 0.5 mmMatching guide cannulaFor use in discrete brain regionsHigh spatial resolutionCauses minimal tissue damageAvailable membrane:Cuprophane, 6kD MWCOMembrane lengths - 1, 2, 3 or 4 mmMembrane diameter - 0.24 mmMatching guide cannulaIdeal for CNS studies in small animalsDesigned for dialysis in transgenic miceLow internal volumeAvailable membrane:Cuprophane, 6kD MWCOMembrane lengths - 1 and 2 mmMembrane diameter - 0.24 mmMatching guide cannula