HUMIC ACID - Laub BioChem

(19)Europäisches PatentamtEuropean Patent OfficeOffice européen des brevets(12) EUROPEAN PATENT SPECIFICATION*EP001007068B1*(11) EP 1 007 068 B1(45) Date of publication and mentionof the grant of the patent:15.06.2005 Bulletin 2005/24(21) Application number: 98906275.7(22) Date of filing: 06.02.1998(51) Int Cl. 7 : A61K 35/78, A61K 39/385,A61K 31/35, A61P 31/12(86) International application number:PCT/US1998/002535(87) International publication number:WO 1998/034629 (13.08.1998 Gazette 1998/32)(54) PROCESS FOR PREPARING SYNTHETIC SOIL-EXTRACT MATERIALS AND MEDICAMENTSBASED THEREONVERFAHREN ZUR HERSTELLUNG VON SYNTHETISCHEN BODENEXTRAKT MATERIALIENUND MEDIKAMENTEN DARAUSMATERIAUX SYNTHETIQUES EXTRAITS DU SOL ET MEDICAMENTS A BASE DE CESMATERIAUXEP 1 007 068 B1(84) Designated Contracting States:AT BE CH DE DK ES FI FR GB GR IE IT LI NL PTSE(30) Priority: 10.02.1997 US 798329(43) Date of publication of application:14.06.2000 Bulletin 2000/24(73) Proprietor: Laub Biochemicals CorporationNewport Beach, CA 92660 (US)(72) Inventor: LAUB, Richard, J.Newport Beach, CA 92660 (US)(74) Representative: Eidelsberg, Victor AlbertCabinet Flechner22, Avenue de Friedland75008 Paris (FR)(56) References cited:EP-A- 0 537 430 EP-A- 0 544 321WO-A-84/03299WO-A-91/06589• H. NAKASHIMA ET AL.: "Lignified materials asmedicinal resources. V. Anti-HIV (HumanImmunodeficiency Virus) activity of somesynthetic lignins" CHEMICAL ANDPHARMACEUTICAL BULLETIN, vol. 40, no. 8,1992, pages 2102-2105, XP000942083• P.K.LAI ET AL.: "Polymeric phenylpropenoidsare the active components in the pine coneextract that inhibit the replication of type-1human immunodeficiency virus in vitro"JOURNAL OF GENERAL AND APPLIEDMICROBIOLOGY, vol. 38, no. 4, 1992, pages303-312, XP000983679• U.EICHHORN, B. HELBIG, R. KLÖCKING ET AL.:"Activity of enzymatically and nonenzymaticallyproduced phenolic polymerizates usingchromium-51 liberation test on coxsackievirusA-9-infected cells" 5TH SESSION OF THEWORKING GROUP ON ANTIVIRAL TESTS OFTHE GESELLSCHAFT FÜR MIKROBIOLOGIEUND EPIDEMIOLOGIE OF EAST GERMANY ANDPHARMAZIE, vol. 40, no. 4, 1985, page 282XP000942104 east berlin• CHEMICAL ABSTRACTS, Vol. 109, No. 7, issued15 August 1988, Abstract No. 53911y, HASSETTet al., "Humic Acids: Synthesis, Properties andAssimilation of Yeast Biomass"; XP002912388 &SOIL BIOL. BIOCHEM., 1988, 20(2), pages227-31.• VIII INTERNATIONAL CONFERENCE ON AIDS/IIISTD WORLD CONGRESS, AMSTERDAM, THENETHERLANDS, 19-24 July 1992, Abstract PuA6152, SCHNEIDER et al., "Inhibition of HIV-1Infection by Synthetic huminates", page 36,XP002910917Note: Within nine months from the publication of the mention of the grant of the European patent, any person may givenotice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed inawritten reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art.99(1) European Patent Convention).Printed by Jouve, 75001 PARIS (FR)