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CURRENT Essentials of Critical Care.pdf

CURRENT Essentials of Critical Care.pdf

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Chapter 20 Pregnancy 291■■■Septic Abortion<strong>Essentials</strong> <strong>of</strong> Diagnosis• Sepsis syndrome following recent spontaneous or induced pregnancytermination• Crampy pelvic pain with serosanguineous or purulent vaginaldischarge occurring within 7 days <strong>of</strong> recent pregnancy terminationor other intrauterine instrumentation• Hematuria and shock can develop rapidly• Abdominal and pelvic exam with tenderness and possible peritonealsigns; dilated cervix, lacerations, products <strong>of</strong> conception,bleeding, discharge• Blood, urine, and cervical specimens should be obtained for culture• Polymicrobial infection with aerobic and anaerobic organisms;Clostridium species important pathogens and suggested by largegram-positive rods on Gram stain• Abdominal radiographs helpful in diagnosis <strong>of</strong> uterine or bowelperforation; gas in myometrium noted on radiographs consistentwith clostridial infection and carries grave prognosis; ultrasoundto assess for presence <strong>of</strong> retained products <strong>of</strong> conception or detectingpossible pelvic abscesses• Likelihood <strong>of</strong> complications increases with later abortions orwith dilation and evacuation proceduresDifferential Diagnosis• Perforated viscus • Puerperal sepsis• Septic shock from prolonged rupture <strong>of</strong> membranesTreatment• Prompt broad-spectrum antibiotics followed by planned uterineevacuation procedure• Hysterectomy may be life saving if clostridial infection suspectedby discolored dusky uterus with myonecrosis or crepitation• Supportive management <strong>of</strong> accompanying complications includingARDS, hypotension, anemia, shock■ PearlSeptic abortion is usually a polymicrobial infection with aerobic andanaerobic bacteria including sexually transmitted pathogens andClostridial species.ReferenceTamussino K: Postoperative infection. Clin Obstet Gynecol 2002;45:562.(PMID: 12048413)

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