Microarray Data Analysis Using BRB-ArrayTools Version 4.2.0 ...

Class comparison toolUnivariate significance test• Compute the univariate p-value pfor each gene,and sort list of genes by smallest p-value. p• In the univariate setting (i.e., testingsignificance of one gene at a time), the p-value pis defined to be the probability of obtaining afalse positive result.• However, once a list of univariately significantgenes is found, it is not clear how many ofthose genes are false positives.85