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Type 2 Diabetes Adult Outpatient Insulin Guidelines - CMA Foundation

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TABLe 17 Oral Medications<br />

Drug class Generic name brand name(s) Mechanism of<br />

action<br />

Dipeptidyl<br />

peptidase-4<br />

(DPP-4) inhibitor<br />

Combination<br />

drugs<br />

Sitagliptin Januvia Enzyme inhibitor,<br />

suppresses<br />

release of<br />

glucagon by<br />

pancreas<br />

Potential side<br />

effects<br />

Runny/stuffy<br />

nose, sore throat,<br />

headache, stomach<br />

pain, diarrhea<br />

Saxagliptin Onglyza Upper respiratory<br />

tract infection,<br />

urinary tract<br />

infection, headache<br />

Linagiptin Tradjenta t blood sugar by<br />

q incretin levels<br />

Metformin HCL/<br />

glyburid, Micro<br />

Glyburide,<br />

Micronized<br />

Metformin/<br />

glipizide<br />

Metformin HCL<br />

/Pioglitazone<br />

HCL<br />

Metformin/<br />

Sitagliptin<br />

Glimepiride /<br />

Pioglitazone<br />

Glimepiride/<br />

Rosiglitazone<br />

Rosiglitazone/<br />

Metformin HCL<br />

Repaglinide/<br />

Metformin HCL<br />

Saxagliptin/<br />

Metformin<br />

Glucovance See mechanism<br />

of action for<br />

Glycron<br />

Glynase<br />

Metaglip<br />

Actopuls Met<br />

Janumet<br />

Duetact<br />

Avadaryl<br />

Avandamet<br />

Prandimet<br />

Kombiglyze XR<br />

each drug in the<br />

combination,<br />

listed separately<br />

above.<br />

Upper respiratory<br />

infection, stuffy or<br />

runny nose, sore<br />

throat, muscle pain,<br />

headache<br />

See side effects for<br />

each drug in the<br />

combination, listed<br />

separately above.<br />

28 <strong>CMA</strong> FoundAtion . diAbetes And CArdiovAsCulAr diseAse Provider reFerenCe guide . july 2011

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