(Teruplug) wound dressing for tooth extraction site.

there were 4 patients who were administered analgesic, while 6 patients were not. Out ofpatients who developed “Marked pain” in either or both sides, all the 9 patients receivedanalgesic. Analgesic was not administered at 1 day and 1 week after tooth extraction.The reason why analgesic was administered or not to patients with bearable pain maydepend on the consciousness of patients for drug in general and correspondence for pain.3) With fixation effectWith fixation effect, as is shown in Table 9, there were 1 completely drop outpatient evaluated as “Dropped out, unknown where it is”, in the indication side at 1 dayafter extraction and 2 such patients in the control side at 1 week after extraction. Ineither time, drop out patients were less, suggesting superiority in fixation effect.Furthermore, as is shown in Table 10, superiority of Teruplug ® was not observed, partlybecause there were less drop out patients. However, fixation effect was largely reducedbecause Teruplug ® drop out patients were patients with single rooted tooth and patientswith displacement to the palatal side (Fig. 4a).As the method for strengthening fixation effect, there are physical characteristicsincluding selection of size or availability to give morphology fitted to the tooth extractioncavity as well as infiltration of blood by pressing with fingers which is performed at thetime of indication. Teruplug ® is a composite made by mixing fibrillar atelo-collagen andheat denatured atelo-collagen with a ratio of 9:1 and has excellent cellular invasivenessand cellular activity, that is, biostability as well as mechanic strength 10) , which maycontribute to good fixation effect.4) Presence or absence of infection after tooth extractionAs is shown in Table 4, infection due to Teruplug ® or Spongel ® after toothextraction was not observed in any patient at 1 day or 1 week after tooth extraction. Thereason may be that subjects were limited to premolars and only healthy teeth wereextracted. Generally, if infection occurs, removal of applied material, cleaning of toothextraction wound, and gargling of the buccal cavity will be sufficient treatment.5) With regard to epithelizationWith regard to epithelization, as is shown in Table 11, at 1 day after extraction19