Chem3D 8.0 Manual - CambridgeSoft

RESEARCH&BioAssay HTSBiological Assay and High Throughput ScreeningBioAssay HTSBioAssay HTS provides scientists with an effective way of managing test results for biological and other kindsof experiments intended to assess the efficacy of compounds. Suitable for both plate-based high throughputscreening assays and smaller-scale lead optimization experiments, BioAssay HTS provides researchers withsimple tools for setting up their models in a database, uploading data, automating calculations and reportingon their findings.User Friendly Assay ManagementEven for the most basic protein assays, the independent and dependent variables used by the biologist to quantifyefficacy can vary substantially from assay to assay. The underlying requirement that follows from this variabilityis for a flexible data management system that can adapt quickly to different assays and biological models.With BioAssay HTS, researchers or IT support staff simply define the observables and calculations thatmake up the assay. The database does the rest. Users can set up unlimited levels of drill-down. This allows users,for example, to click an IC50 and see a graph of percent inhibition versus concentration. Click again, and thesoftware displays the original triplicate results, with outliers marked. The software even supports complex invivo models.Automated CurveFitting & Data AnalysisFlexible AssayDefinition Tools