View PowerPoint Presentation - Vision Research Coordinating Center

More documents

Recommendations

Info

The OHTS Entry Criteria Age 40 - 80Normal visual fields– Humphrey 30-2Normal optic discsUntreated IOP:– 24 to 32 mmHg in qualifying eye– 21 to 32 mmHg in fellow eyeJune, 2002
Patient found eligible for OHTS• Eligible untreated IOPs on 2 visits• 2 sets of normal & reliable HVFs per VFRC• Optic discs judged normal by ODRCRandomizationMedicationTopical treatment to lower IOP 20%and IOP < 24 mm HgAdjust therapy iftarget not metObservationNo topical treatment to lower IOPMonitoringHumphrey 30-2 q6 monthsStereoscopic disc photos annuallyReproducible Abnormality3 consecutive visual fields and/or 2 consecutive sets of optic disc photographsas determined by masked readers at ODRC or VFRCJune, 2002POAGVisual field and/or optic disc changes attributed toPOAG by masked Endpoint Committee
Page 1 and 2: The Ocular HypertensionTreatment St
Page 3 and 4: Why did we do this study?Don’t we
Page 5: Ocular Hypertension Treatment Study
Page 9 and 10: Baseline Characteristics by Randomi
Page 15 and 16: IOP By RaceMedicationObservationAfr
Page 17 and 18: Progress and Outcome of Study Parti
Page 19 and 20: Proportion POAG1 st Visual Field PO
Page 21 and 22: First POAG Endpoint per Participant
Page 23 and 24: Treatment perhaps less protectivein
Page 25 and 26: Percent Reporting Changes inIris, L
Page 27 and 28: Borderline Safety DifferencesBetwee
Page 29 and 30: Significant Baseline Predictive Fac
Page 31 and 32: Significant Baseline Predictive Fac
Page 33 and 34: POAG Endpoints by Central Corneal T
Page 35 and 36: 60-year-old WF IOP 24 / 24 C/D rati
Page 37 and 38: 60-year-old WF IOP 28 / 28 C/D rati
Page 39 and 40: 72-year-old BM IOP 25 / 25 C/D rati
Page 41 and 42: Weaknesses1. Convenience sample rat
Page 43 and 44: Possible Misinterpretations of OHTS
Page 45: OHTS Clinical CentersBascom Palmer

View PowerPoint Presentation - Vision Research Coordinating Center

You also want an ePaper? Increase the reach of your titles

Delete template?

Save as template?