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Patient found eligible for OHTS• Eligible untreated IOPs on 2 visits• 2 sets of normal & reliable HVFs per VFRC• Optic discs judged normal by ODRCRandomizationMedicationTopical treatment to lower IOP 20%and IOP < 24 mm HgAdjust therapy iftarget not metObservationNo topical treatment to lower IOPMonitoringHumphrey 30-2 q6 monthsStereoscopic disc photos annuallyReproducible Abnormality3 consecutive visual fields and/or 2 consecutive sets of optic disc photographsas determined by masked readers at ODRC or VFRCJune, 2002POAGVisual field and/or optic disc changes attributed toPOAG by masked Endpoint Committee