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Protein Engineering Protocols - Mycobacteriology research center

Protein Engineering Protocols - Mycobacteriology research center

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22 Kono et al.68. Wolf, E. and Kim, P. S. (1999) Combinatorial codons: a computer program toapproximate amino acid probabilities with biased nucleotide usage. <strong>Protein</strong> Sci.8, 680–688.69. Wang, W. and Saven, J. G. (2002) Designing gene libraries from protein profilesfor combinatorial protein experiments. Nucleic Acids Res. 30, e120.70. Eriksson, A. E., Baase, W. A., Zhang, X. J., Heinz, D. W., Blaber, M., Baldwin, E. P.,and Matthews, B. W. (1992) Response of a protein structure to cavity-creatingmutations and its relation to the hydrophobic effect. Science 255, 178–183.71. Axe, D. D., Foster, N. W., and Fersht, A. R. (1996) Active barnase variants withcompletely random hydrophobic cores. Proc. Natl. Acad. Sci. USA 93, 5590–5594.72. Voigt, C. A., Mayo, S. L., Arnold, F. H., and Wang, Z. G. (2001) Computationalmethod to reduce the search space for directed protein evolution. Proc. Natl.Acad. Sci. USA 98, 3778–3783.

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