Oxidative Phosphorylation - Ecu

Complex V (ATP Synthase; F F ATPase)o 1 A Rotating Molecular Motor• Consumes the energy in the proton gradientto synthesize ATP from ADP.• Couples the phosphorylation of ADP to theoxidation of substrates in the mitochondrion(hence oxidative phosphorylation).• Mechanism of ATP synthesis is now known, aswell as the x-ray crystal structure. Paul Boyerand John Walker won the Nobel Prize in 1997for this work.