Oxidative Phosphorylation - Ecu

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Control of Ox. Phos.:Control is tied to the cellular energy demand.This is sensed largely by [ATP].As ATP is consumed in the cytosol, ADP istransported into the matrix (in antiport withATP) by the adenine nucleotide translocase.Electron transport, strictly coupled to [ADP]accelerates.
Since ATP carries a charge of -4 and ADPcarries a charge of -3, transporting an ATPfrom the matrix to the cytosol results inaddition of one negative charge on thecytoplasmic side of the inner mitochondrialmembrane.This is equivalent to moving a proton backinto the matrix from the cytosol.It takes 3 protons moving through Fo toproduce 1 ATP. Taking into account movingthis ATP to the cytosol, we can conclude thatit takes a total of 4 protons/ATP synthesized.
Page 1 and 2: OxidativePhosphorylation
Page 3 and 4: Glycerophosphate Shuttle(skeletal m
Page 5 and 6: • Oxidative Phosphorylation: NADH
Page 7 and 8: Meaning of the standard reduction p
Page 9 and 10: Electron Transport Through Complex
Page 11 and 12: Complex III (Cytochrome bc Complex)
Page 13 and 14: Complete Q Cycle:intermembranespace
Page 15 and 16: Complex V (ATP Synthase; F F ATPase
Page 18 and 19: Binding Change Mechanism (Boyer):
Page 20 and 21: Uncouplers:• Lipid-soluble weak a
Page 24 and 25: How many protons are translocatedpe

Oxidative Phosphorylation - Ecu

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