Oxidative Phosphorylation - Ecu

Binding Change Mechanism (Boyer):• F1 has three interacting and conformationallydistinct active sites.• Protons bind to aspartate residues in the csubunit rotor and cause it to rotate.• This rotations causes the γ subunit to turnrelative to the three β subunit nucleotide sitesof F1, changing the conformation of each insequence, so that ADP is first bound, thenphosphorylated, then released.