1 Arjan DE GROOT cv Publications - CEA

Arjan DE GROOTLEMiRE, iBEB, UMR 6191, CEA Cadarache13108 Saint Paul Lez DuranceTel +33 (0)4 42 25 37 86 - nicolaas.degroot@cea.frcv2004 - Chercheur CEA, LEMiRE, IBEB, CEA CadaracheMécanismes de tolérance de Deinococcus aux radiations et à la dessiccation2001-2004 Post-doctorat au LCCP, IBS, Grenoble (3 ans)Étude structurale par cristallographie des récepteurs nucléaires de la drosophile et autres animaux2000 Post-doctorat au BBSI, DBMS, CEA Grenoble (6 mois)Mécanismes de régulation de la virulence de Pseudomonas aeruginosa: expression des gènes dusystème de sécrétion type III2000 Post-doctorat au LISM, IBSM, CNRS Marseille (6 mois)Mécanismes de sécrétion des facteurs de virulence d'une bactérie pathogène opportunistePseudomonas aeruginosa1998-1999 Post-doctorat au LEMiR, DEVM, CEA Cadarache (7 mois)Variation de phase chez Pseudomonas brassicacearum : mécanisme de sécrétion de protéase(s) etlipase(s)1996-1999 Post-doctorat à l’Université d’Utrecht et au LISM, IBSM, CNRS Marseille (3 ans)« Pseudomonads as enzyme factories »: Characterization of protein-protein interactions within theXcp protein secretion machinery1995 Doctorat de Biologie Cellulaire et Microbiologie - Université d’Utrecht, Pays-BasResponsable Dr J. TOMMASSENMolecular characterization of protein secretion in plant growth-promoting Pseudomonas putidaPublicationsGoosen N., Horsman H.P.A., Huinen R.G.M., De Groot A. & van de Putte P. 1989. Genes involved in thebiosynthesis of PQQ from Acinetobacter calcoaceticus. Antonie van Leeuwenhoek 56, 85-91.De Groot A.*, Filloux A. & Tommassen J. 1991. Conservation of xcp genes involved in the two-step secretionprocess in different Pseudomonas species and other gram-negative bacteria. Mol. Gen. Genet. 229, 278-284.Frenken L.G.J., De Groot A., Tommassen J. & Verrips C.T. 1993. Role of the lipB gene product in the folding ofthe secreted lipase of Pseudomonas glumae. Mol. Microbiol. 9, 591-599.De Groot A.*, Heijnen I., de Cock H., Filloux A. & Tommassen J. 1994. Characterization of type IV pilus genes inplant growth-promoting Pseudomonas putida WCS358. J. Bacteriol. 176, 642-650.De Groot A., Krijger J.-J., Filloux A. & Tommassen J. 1996. Characterization of type II protein secretion (xcp)genes in the plant growth-stimulating Pseudomonas putida strain WCS358. Mol. Gen. Genet. 250, 491-504.Braun P., De Groot A., Bitter W. & Tommassen J. 1998. Secretion of elastinolytic enzymes and their propeptidesby Pseudomonas aeruginosa. J. Bacteriol. 180, 3467-3469.De Groot A., Gerritse G., Tommassen J., Lazdunski A. & Filloux A. 1999. Molecular organization of the xcp genecluster in Pseudomonas putida: absence of an xcpX (gspK) homologue. Gene 226, 35-40.De Groot A., Koster M., Gérard-Vincent M., Gerritse G., Lazdunski A., Tommassen J. & Filloux A. 2001.Exchange of Xcp (Gsp) secretion machineries between Pseudomonas aeruginosa and Pseudomonas alcaligenes:species-specificity unrelated to substrate recognition. J. Bacteriol. 183, 959-967.1

Chabeaud P., De Groot A., Bitter W., Tommassen J., Heulin T. & Achouak W. 2001. Phase-variable expression ofan operon encoding extracellular alkaline protease, serine protease homolog, and lipase in Pseudomonasbrassicacearum. J. Bacteriol. 183, 2117-2120.Dacheux D., Epaulard O., De Groot A., Guery B., Leberre R., Attree I., Polack B. & Toussaint B. 2002. Activationof the Pseudomonas aeruginosa type III secretion system requires an intact pyruvate dehydrogenase aceAB operon.Infect. Immun. 70, 3973-3977.De Vrind J., De Groot A., Brouwers G.-J., Tommassen J. & de Vrind-de Jong E. 2003. Identification of a novelGsp-related pathway required for secretion of the manganese-oxidizing factor of Pseudomonas putida strain GB-1.Mol. Microbiol. 47, 993-1006.Nálezková M., De Groot A., Graf M., Gans P. & Blanchard L. 2005. Overexpression and purification ofPyrococcus abyssi phosphopantetheine adenylyltransferase (PPAT) from an optimized synthetic gene for NMRstudies. Protein Expr. Purif. 39, 296-306.Bouton D., Escriva H., de Mendonça R.L., Glineur C., Bertin B., Noël C., Robinson-Rechavi M., De Groot A.,Cornette J., Laudet V. & Pierce R.J. 2005. A conserved retinoid X receptor (RXR) from the mollusk Biomphalariaglabrata transactivates transcription in the presence of retinoids. J. Mol. Endocrinol. 34, 567-582.De Groot A.*, Chapon V., Servant P., Christen R., Fischer-Le Saux M., Sommer S. & Heulin T. 2005.Deinococcus deserti sp. nov., a gamma-radiation tolerant bacterium isolated from the Sahara desert. Int. J. Syst.Evol. Microbiol. 55, 2441-2446.De Groot A.*, de Rosny E., Juillan-Binard C., Ferrer J.-L., Laudet V., Pierce R.J., Pebay-Peyroula E., Fontecilla-Camps J. & Borel F. 2005. Crystal structure of a novel tetrameric complex of agonist-bound ligand-binding domainof Biomphalaria glabrata Retinoid X Receptor. J. Mol. Biol. 354, 841-853.De Rosny E., De Groot A., Juillan-Binard C., Gaillard J., Borel F., Pebay-Peroula E., Fontecilla-Camps J.C. &Jouve H.M. 2006. Drosophila nuclear receptor E75 is a thiolate hemoprotein. Biochemistry 45, 9727-9734.Arts J. ◊ , De Groot A. ◊ , Ball G., Durand E., El Khattabi M., Filloux A., Tommassen J. & Koster M. 2007.Interaction domains in the Pseudomonas aeruginosa type II secretory apparatus component XcpS. Microbiology153, 1582-1592.◊ Co-premier auteurGutsche I., Vujicic-Zagar, A., Servant P., Vannier F., Castaing B., Gallet B., Heulin T., De Groot A., Sommer S. &Serre L. 2008. Complex oligomeric structure of DdrA: A protein required for the extreme radiotolerance ofDeinococcus. Biochim. Biophys. Acta 1784, 1050-1058.De Rosny E., De Groot A., Juillan-Binard C., Borel F., Suarez C., Lepape L., Fontecilla-Camps J.C. & Jouve H.M.2008. DHR51, the Drosophila melanogaster homolog of the human Photoreceptor cell-specific nuclear receptor, isa thiolate heme-binding protein. Biochemistry 47, 13252-13260.Borel F., De Groot A., Juillan-Binard C., De Rosny E., Laudet V., Pebay-Peyroula E., Fontecilla-Camps J.C.,Ferrer J.-L. . 2009. Crystal structure of the ligand-binding domain of the retinoid X receptor from the ascidianPolyandrocarpa misakiensis. Proteins 74, 538-542.Vujicic-Zagar A., Dulermo R., Le Gorrec M., Vannier F., Servant P., Sommer S., De Groot A. & Serre L. 2009.Crystal structure of the IrrE protein, a central regulator of DNA damage repair in Deinococcaceae. J. Mol. Biol.386, 704-716.De Groot A.*, Dulermo R., Ortet P., Blanchard L., Guérin P., Fernandez B., Vacherie B., Dossat C., Jolivet E.,Siguier P., Chandler M., Barakat M., Dedieu A., Barbe V., Heulin T., Sommer S., Achouak W. & Armengaud J.2009. Alliance of proteomics and genomics to unravel the specificities of Sahara bacterium Deinococcus deserti.Plos Genetics 5(3):e1000434.Dulermo R., Fochesato S., Blanchard L. & De Groot A.* 2009. Mutagenic lesion-bypass and two functionallydifferent RecA proteins in Deinococcus deserti. Mol. Microbiol. 74 (1), 194-208.2