WTZ Cancer Center Director Univ. Prof. Dr. med. Angelika Eggert ...

2. Coordinators:
Prof. Dr. med. Erich Gulbins/
Dept. of Molecular Biology
6. Selected publications 2002-2008
Grassmé H., Jendrossek V., Riehle A., von Kürthy G., Berger J., Schwarz H., Weller M.,
Kolesnick R., Gulbins E. (2003). Host defense against P. aeruginosa requires
ceramide-rich membrane rafts.
Nature Medicine 9, 322-330. IF 30.6
Grassmé H., Cremesti A., Kolesnick R., Gulbins E. (2003). Ceramide-mediated clustering is
required for CD95-DISC formation.
Oncogene 22, 5457-5470. IF 6,4
Göggel R., Winoto-Morbach S., Vielhaber G., Imai Y., Lindner K., Brade L., Brade H., Ehlers S.,
Slutsky A.S., Schütze S., Gulbins E., Uhlig S. (2004). Pulmonary edema: a novel effector function
for acid sphingomyelinase and ceramide.
Nature Medicine 10, 155-160. IF 30.6
Szabo I., Bock J., Jekle A., Soddemann M., Adams C., Lang F., Zoratti M., Gulbins E. (2005).
A novel potassium channel in lymphocyte mitochondria.
J. Biol. Chem. 280, 12790-12798. IF 6.5
Dumitru C., Gulbins E. (2006). TRAIL/DR5-induced apoptosis by the acid sphingomyelinase,
ceramide and ceramide-enriched membrane platforms.
Oncogene, 25, 5612-5625. IF 6.4
Lang PA, Schenck M, Nicolay JP, Becker JU, Kempe DS, Lupescu A, Koka S, Eisele K,
Klarl BA, Rübben H, Schmid KW, Mann K, Hildenbrand S, Hefter H, Huber SM, Wieder T,
Erhardt A, Häussinger D, Gulbins E, Lang F. (2007) Liver cell death and anemia in Wilson
disease involve acid sphingomyelinase and ceramide.
Nature Medicine 13:164-70. IF 30,6
Rebillard A, Tekpli X, Meurette O, Sergent O, LeMoigne-Muller G, Vernhet L, Gorria M,
Chevanne M, Ch i t M K i B C ill L G lbi E L di G DDi h B it l MT (2007)
Christmann M, Kaina B, Counillon L, Gulbins E, Lagadic-Gossmann D, Dimanche-Boitrel MT.
(2007) Cisplatin-induced apoptosis involves membrane fluidification via inhibition of NHE1 in
human colon cancer cells.
Cancer Res. 67:7865-74. IF 8,7
Teichgräber V., Ulrich M., Endlich N., Riethmüller J., Wilker B., De Oliveira-Munding C.,
van Heeckeren A. M., Barr M. L., von Kurthy G., Schmid K. W., Weller M., Tümmler B., Lang F.,
Grassme H., Döring G. Gulbins E. (2008). Ceramide accumulation mediates inflammation, cell
death and infection susceptibility in cystic fibrosis.
Nature Medicine. 14, 382-91 IF 30,6
Eisenhardt A, Frey U, Tack M, Rosskopf D, Lümmen G, Rübben H, Siffert W. Expression analysis
and potential functional role of the CXCR4 chemokine receptor in bladder cancer.
Eur Urol. 2005;47:111- 117.
Frey UH, Eisenhardt A, Lümmen G, Rübben H, Jöckel KH, Schmid KW, Siffert W. The T393C
polymorphism of the G alpha s gene (GNAS1) is a novel prognostic marker in bladder cancer.
Cancer Epidemiol Biomarkers Prev. 2005;14:871-7. IF 2.6 IF 4.5