WTZ Cancer Center Director Univ. Prof. Dr. med. Angelika Eggert ...

2. Coordinator
Klein-Hitpass, Ludger, PD Dr. rer. nat.
Biochip-Labor, Institute for Cell Biology – Tumor Research
6. Selected publications 2002 - 2008
Duerig, J., Nueckel, H., Huettmann, A., Kruse, E., Hoelter, T., Halfmeyer, K., Fuehrer, A.,
Rudolph, R., Kalhori, N., Nusch, A., Deaglio, S., Malavasi, F., Moeroey, T., Klein-Hitpass, L.,
Duehrsen, U. (2002), Expression of ribosomal and translation-associated genes is correlated
with a favorable clinical course in chronic lymphocytic leukaemia,
Blood 101, 2748-55, 2002 IF 10.1
Horsthemke B, Nazlican H, Hüsing J, Klein-Hitpass L, Claussen U, Michel S, Lich C, Gillessen-
Kaesbach G, Buiting K (2003), Somatic mosaicism for maternal uniparental disomy 15 in a girl
with Prader-Willi syndrome: confirmation by cell cloning and identification of candidate
downstream genes,
Hum Mol Genet. 12, 2723-2732, 2003 IF 7.8
Dürig J, Nückel H, Cremer M, , Führer A, Halfmeyer K, Fandrey J, Möröy T, Klein-Hitpass L,
Dührsen U (2003), ZAP-70 expression is a prognostic factor in chronic lymphatic leukemia,
Leukemia 17, 2426-2434, 2003 IF 6.6
Thomas H, Senkel S, Erdmann S, Arndt T, Turan G, Klein-Hitpass L, Ryffel GU. (2004), Pattern
of genes influenced by conditional expression of the transcription factors HNF6, HNF4alpha and
HNF1beta in a pancreatic beta-cell line.
Nucleic Acids Res. 32, e150, 2004 IF 7.6
Zeng H, Yücel R, Kosan C, Klein-Hitpass L, Möröy T. (2004), Transcription factor Gfi1 regulates
self-renewal and engraftment of hematopoietic stem cells.
EMBO J. 23, 4116-4125, 2004 IF 10.1
Grasemann C, Gratias S, Stephan H, Schüler A, Schramm A, Klein-Hitpass L, Rieder H,
Schneider S, Kappes F, Eggert A, Lohmann DR (2005), Gains and overexpression identify
DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma,
Oncogene 24, 6441-6449, 2005. IF 6.9
Lucas B, Grigo K, Erdmann S, Lausen J, Klein-Hitpass L, Ryffel GU (2005). HNF4α reduces
proliferation of kidney cells and affects genes deregulated in renal cell carcinoma,
Oncogene 24, 6418-6431, 2005. IF 6.9
Schramm A, Schulte JH, Klein-Hitpass L, Havers W, Sieverts H, Berwanger B, Christiansen H,
Warnat P, Brors B, Eils J, Eils R, Eggert A. (2005). Prediction of clinical outcome and biological
characterization of neuroblastoma by expression profiling,
Oncogene 24, 7902-7912, 2005. IF 6.9
Hüttmann A, Klein-Hitpass L, Thomale J, Deenen R, Carpinteiro A, Nückel H, Ebeling P,
Führer A, Edelmann J, Sellmann L, Dührsen U, Dürig J. Gene expression signatures separate
B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38
expression status.
Leukemia. 2006;20:1774-82. IF 6.6
Gratias S, Rieder H, Ullmann R, Klein-Hitpass L, Schneider S, Bölöni R, Kappler M, Lohmann
DR. Allelic loss in a minimal region on chromosome 16q24 is associated with vitreous seeding
of retinoblastoma.
Cancer Res. 2007;67:408-16. IF 8.4
Dürig J, Bug S, Klein-Hitpass L, Boes T, Jöns T, Martin-Subero JI, Harder L, Baudis M,
Dührsen U, Siebert R. Combined single nucleotide polymorphism-based genomic mapping
and global gene expression profiling identifies novel chromosomal imbalances, mechanisms
and candidate genes important in the pathogenesis of T-cell prolymphocytic leukemia with
inv(14)(q11q32).
Leukemia. 2007;21:2153-63. IF 6.6