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WTZ Cancer Center Director Univ. Prof. Dr. med. Angelika Eggert ...

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2. Coordinator<br />

Kurt Werner Schmid, MD, MRCPath,<br />

<strong>Prof</strong>essor of Pathology, <strong>Director</strong>,<br />

Institute of Pathology and Neuropathology<br />

6. Selected publications 2005 – 2008<br />

Lehnerdt GF, Franz P, Zaqoul A, Schmitz KJ, Grehl S, Lang S, Schmid KW Siffert W, Jahnke K,<br />

Frey UH. Overall and relapse-free survival in oropharyngeal and hypopharyngeal squamous cell<br />

carcinoma are associated with genotypes of T393C polymorphism of the GNAS1 gene.<br />

Clin <strong>Cancer</strong> Res. 2008; 14: 1753-1758. IF 6.2<br />

Schmitz KJ, Wohlschlaeger J, Lang H, Sotiropoulos, GC, Malago M, Steveling K, Reis H,<br />

Cicinnati VR, Schmid KW, Baba HA. Activation of the ERK and AKT signalling pathway predicts<br />

poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated<br />

with hepatitis C virus infection<br />

J Hepatol. 2008; 48: 83-90. IF 6.1<br />

Bachmann HS, Otterbach F, Callies R, Nuckel H, Bau M, Schmid KW, Siffert W, Kimmig R. The<br />

AA Genotype of the Regulatory BCL2 Promoter Polymorphism (938>A) Is Associated with a<br />

Favorable Outcome in Lymph Node Negative Invasive Breast <strong>Cancer</strong> Patients.<br />

Clin <strong>Cancer</strong> Res. 2007; 13:5790-7. IF 6.2<br />

Grabellus F, Ebeling P, Worm K, Sheu SY, Antoch G, Frilling A, Schmid KW. Double resistance<br />

to imatinib and AMG 706 caused by multiple acquired KIT exon 17 mutations in a gastrointestinal<br />

stromal tumour.<br />

Gut. 2007; 56:1025-6. IF 9.0<br />

Schmitz KJ, Lang H, Frey UH, Sotiropulos GC, Wohlschlaeger J, Reis H, Takeda A, Siffert W,<br />

Schmid KW, Baba HA. The GNAS1 T393C polymorphism is associated with the clinical course<br />

In patients with intrahepatic cholangiocarcinoma.<br />

Neoplasia 2007; 9:159-65. IF 4.9<br />

Sheu S-Y, Handke S, Bröcker-Preuss M, Görges R, Frey UH, Ensinger C, Öfner D, Farid NR,<br />

Siffert W, Schmid KW. The C allele of the GNB3 C825T polymorphism of the G protein β3-<br />

subunit is associated with an increased risk for the development of oncocytic thyroid tumours.<br />

J Pathol. 2007; 211:60-66. IF 5.8<br />

Frey UH, Lümmen G, Jäger T, Jöckel K-H, Schmid KW, Rübben H, Siffert W, Eisenhardt A.<br />

The GNAS1 T393C polymorphism predicts the clinical outcome in patients with clear cell renal<br />

cell carcinoma.<br />

Clin <strong>Cancer</strong> Res. 2006; 12:759-63 IF 5.6<br />

Sheu S-Y, Görges R, Ensinger C, Öfner D, Farid NR, Siffert W, Schmid KW. Different genotype<br />

distribution of the GNB3 C825T polymorphism of the G protein ß3 subunit in adenomas and<br />

differentiated thyroid carcinomas of follicular cell origin.<br />

J Pathol 2005; 207:430-435 IF 5.3<br />

Gashaw I, Grummer R, Klein-Hitpass L, Dushaj O, Bergmann M, Brehm R, Grobholz R,<br />

Kliesch S, Neuvians TP, Schmid KW, Ostau CV, Winterhager E. Gene signatures of testicular<br />

seminoma with emphasis on expression of ets variant gene 4.<br />

Cell Mol Life Sci. 2005; 62:2359-68. IF 4.8<br />

Frey UH, Alakus H, Wohlschlaeger J, Schmitz KJ, Winde G, van Calker HG, Jaeckel KH, Siffert<br />

W, Schmid KW. GNAS1 T393C polymorphism and survival in patients with sporadic colorectal<br />

cancer.<br />

Clin <strong>Cancer</strong> Res. 2005; 15:5071-7. IF 5.6

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