VIRAL INFECTION - Faculty of Medicine
VIRAL INFECTION - Faculty of Medicine
VIRAL INFECTION - Faculty of Medicine
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Human papilloma virus (HPV)• Most common causes <strong>of</strong> sexuallytransmitted infection (STI) in the world• HPV types cause benign skin wart,anogenital warts, anogenital cancerHuman papilloma virus (HPV)• Transmitted by skin-to-skin contactduring sexual intercourse• Treated by electrocautery, lasertreatment• Histology : koilocytosis <strong>of</strong> infected cells• Warts: proliferative squamous epitheliumproducing nodules or flat lesionsHuman papilloma virus (HPV)Skin warts• Skin warts- HPV types 1,2- common warts (verruca vulgaris):hands, trunk, extremities- plantar warts: plantar- no associated with cancerHuman papilloma virus (HPV)Anogenital warts(condylomata acuminata)• Anogenital warts (condyloma acuminatum)- HPV types 6,11- warts at penis, vulva, vagina, anus- no associated with cancer• Anogenital cancer (squamous cell carcinoma)- HPV types 16,18,31,45- cause <strong>of</strong> cancer <strong>of</strong> anus, vulva, cervixand penis