Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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Preventative SurgeryProphylactic Mastectomy•At least 90% risk reduction•Subcutaneous mastectomy not recommendedProphylactic Oophorectomy•Recommended after childbearing complete•With or without hysterectomy•HRT issues for young women•Shown to reduce BREAST cancer risk byat least 50% in pre-menopausal women•Reduces <strong>Ovarian</strong> cancer risk dramatically•Residual risk for primary peritoneal carcinoma
BR 51Stom 53 Brain 50Liver 72BR 29BR 58BR 35
Page 1 and 2: Ovarian Cancer: Genetic Counseling
Page 3 and 4: Family History of Ovarian Cancer•
Page 5 and 6: BRCA1-Associated Associated Cancers
Page 7 and 8: BRCA2-Associated Associated Cancers
Page 9: Clinical Management ofBRCA Mutation
Page 13 and 14: BR 51OV 53 Brain 50OV 72B1POSB1NEGB
Page 15 and 16: Risk Reduction from removing ovarie
Page 17 and 18: Other Benefits of Prophylactic Ooph
Page 19 and 20: BRCA1 familyProstate 60Colon 60B1B1
Page 21 and 22: Features That Indicate IncreasedLik
Page 23 and 24: Amsterdam Criteria• 3 or more rel
Page 25 and 26: Genetic Testing forCancer Susceptib
Page 27 and 28: Genetic Testing for Cancer Risk•
Page 29: Concerns regarding discrimination

Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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