Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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Familial Risk for Ovarian• Major risk and minor risk genes• Hereditary cancer risk• Sometimes source of cancer risk can be identified• Targeted management plan to lower risk andmaximize chances for early detection
Family History of Ovarian Cancer• Average woman risk of ovarian cancer is 1-2% 1• One close relative with ovarian cancer• Mother, sister• Lifetime risk is 3-5% 3• Two close relatives with ovarian cancer• Lifetime risk is about 20%
Page 1: Ovarian Cancer: Genetic Counseling
Page 5 and 6: BRCA1-Associated Associated Cancers
Page 7 and 8: BRCA2-Associated Associated Cancers
Page 9 and 10: Clinical Management ofBRCA Mutation
Page 11 and 12: BR 51Stom 53 Brain 50Liver 72BR 29B
Page 13 and 14: BR 51OV 53 Brain 50OV 72B1POSB1NEGB
Page 15 and 16: Risk Reduction from removing ovarie
Page 17 and 18: Other Benefits of Prophylactic Ooph
Page 19 and 20: BRCA1 familyProstate 60Colon 60B1B1
Page 21 and 22: Features That Indicate IncreasedLik
Page 23 and 24: Amsterdam Criteria• 3 or more rel
Page 25 and 26: Genetic Testing forCancer Susceptib
Page 27 and 28: Genetic Testing for Cancer Risk•
Page 29: Concerns regarding discrimination

Ovarian Cancer: Genetic Counseling and Testing, Screening and ...

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