PDF, Patent Landscape Report on Atazanavir - WIPO
PDF, Patent Landscape Report on Atazanavir - WIPO
PDF, Patent Landscape Report on Atazanavir - WIPO
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
TWO DRUGS DIRECTED AT THE SAME TARGETMultiple drugs exist in the HIV-protease inhibitor class. Drugs affecting the same target inthe HIV replicati<strong>on</strong> pathway are often used together to reduce the ability of HIV to developdrug resistance by developing variants. Treating with two drugs attacking the same targetreduces the chances that effective variants will arise, or as in the example shown in Figure38, help to overcome resistance that has begun to develop.Figure 38. Combinati<strong>on</strong> using two PI drugs and aimed at rescue43